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IRCT20130911014630N6 IRCT 2019-08-26 Mazandaran University of Medical Sciences Evaluation of Therapeutic Effect of Descurainia sophia on the patients with hyperthyroidism ETEDH Evaluation of Therapeutic Effect of glucoseinolate extract of Descurainia sophia (L.) Webb ex Prantl on the improvement of patients with hyperthyroidism who are treated with methimazole;Pilot study Double Blinded and Placebo-Controlled Clinical Trial 2019-05-24 anticipated 16 Complete https://irct.ir/trial/34626 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: First, we divide the patients into the two groups according to the number of attending the clinic and using the random number table, Blinding description: According to the code assigned to each of the products in the previous stage, we assign a code to each patient so that the patient and the doctor are not aware of the type of capsule they are consuming. 0 (exploratory trials) Hyperthyroidism. Intervention 1: Intervention group: methimazole with a dose of 10 to 20 mg per day plus a capsules containing 350 mg of extract of the plant during 3months. Intervention 2: Control group: methimazole with a dose of 10 to 20 mg per day plusplacebo capsules during 3months. Yes - There is a plan to make this available What will be shared: Results from clinical trials When: Start access after printing the article To whom: Access for scholars working in academic institutions Conditions: Use of results is allowed only by mentioning its source Where to obtain: azadbakhtm@hotmail.com How to obtain: Request from the researcher Comments:
public Fatemeh Farzameh
Iran, Mazandaran province, Sari city,Prophet Mohammad Medical Sciences Complex,Mazandaran faculty of pharmacy
Sari Iran (Islamic Republic of) - . atena.farzameh1997@gmail.com Mazandaran University of Medical Sciences scientific Mohamad Azadbakht
Iran,Mazandran province,sari city,Prophet Mohammad Medical Sciences Complex,Mazandaran faculty of pharmacy
Sari Iran (Islamic Republic of) 48188-69378 +98 911 151 3032 Mazadbakht@gmail.com Mazandaran University of Medical Sciences Iran (Islamic Republic of) Age between twenty to sixty years Patients with a higher level of FT4 hormones have a parity of 17 pg /L Patients with a FT3 serum level Larger than equal to 5.7 pg/ml Patients with a lower serum TSH level equal to MU / I0.4 20 years 60 years Female Patients with a history of underlying illness, such as diabetes or hypertension or liver failure, such as cirrhosis of the liver and kidney or heart disease, according to patients referenced Use other medications Use cigarettes right now Alcoholism Pregnant patients Lactating patients Patients who have taken an antithyroid drug for the last three months Patient with ALT levels are twice the normal range Patients who are required to receive other medications for the treatment of other illness during the study Patients who experience side effects such as itching or headache or allergies to the drug Requesting a patient or his family to leave the study E05.9 Thyrotoxicosis, unspecified Treatment - Drugs Placebo Intervention group: methimazole with a dose of 10 to 20 mg per day plus a capsules containing 350 mg of extract of the plant during 3months Control group: methimazole with a dose of 10 to 20 mg per day plusplacebo capsules during 3months Level of thyroid hormones. Timepoint: First of the study (before the intervention) and 30, 60 and 90 days after the start of the capsule. Method of measurement: Collection of questionnaires and laboratory tests and periodic clinical examinations. Mazandaran University of Medical Sciences Approved 2019-05-01 Ethics committee of Mazandaran University of Medical Sciences Moalem sq.Mazandaran University of Medical Science Sari Mazandaran Iran (Islamic Republic of)