IRCT20170202032367N4 IRCT 2019-12-18 Tehran University of Medical Sciences The effect of L-arginine supplementation in patients with congestive heart failure The effect of L-Arginine supplementation on the levels of glucose, N-Terminal pro Brain Natriuretic Peptide (NT pro-BNP), lipids, blood pressure, ejection fraction, quality of life and rehabilitation in patients with congestive heart failure. 2018-10-23 anticipated 44 Complete https://irct.ir/trial/34323 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Regarding to the diabetic status, patients were randomly classified into two groups to receive either L-arginine-supplement or placebo. Stratified Blocked Randomization method was used to randomly assign patients to study groups, Blinding description: In order to blinding the allocation, similar boxes of L-arginine or placebo were labeled by an independent person as A or B. Patients, the main researcher and the cardiologist were blind in this study. 3 congestive heart failure. Intervention 1: Intervention group: L-Arginine supplement (3 g / day) after breakfast, lunch, dinner for 10 weeks.take it orally and this supplement produced by Karen company. Intervention 2: Placebo group: Oral placebo (including maltodextrin) 3 times daily after breakfast, lunch, dinner for 10 weeks orally. Placebo is quite similar in appearance, color, odor and taste. Produced by Karen. No - There is not a plan to make this available Justification or reason for not sharing IPD is The patient's anthropometric and clinical information is confidential