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IRCT20170705034908N3 IRCT 2019-03-17 Tabriz University of Medical Sciences Comparison of the Effectiveness of iron injectable drugs in anemia correction and blood transfusion rate Comparison of the Effectiveness of Ferric carboxymaltose versus Iron sucrose in Anemia correction /impact on Transfusion Requirements in patients undergoing cardiac surgery 2019-02-20 anticipated 66 Complete https://irct.ir/trial/34058 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: The permuted balanced block randomizatio method is used with four blocks. This is done by study colleagues who are not present in the therapeutic field. Random sequences are presented in envelopes depending on the original researcher of the study. 2 iron deficiency anaemia In patients undergoing cardiac surgery. Intervention 1: Iron sucrose group:Patients in this group receive 1000 mg of an Iron sucrose drug by injection and within 3 weeks of surgery. Intervention 2: Ferric carboxymaltose group: Patients in this group receive 1000 mg of Ferricarboxymaltose by injection and within 3 weeks of surgery. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.
public Elham KHalaf Adeli
Blood Transfusion Center,Hemmat Blvd
Tehran Iran (Islamic Republic of) 11111111111111 +98 21 82050 elhamadeli@gmail.com Blood Transfusion Center scientific Fatemeh Ramezani
No 2,Emam Hosine Ave,Ashrafi Esfahani Blvd.
Tehran Iran (Islamic Republic of) 1473179637 +98 21 4442 4414 forooghramzani@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) People over the age of 18 who are undergoing cardiac surgery for the first time. Men with Hb<13 and women with Hb<12 and (ferritin 100-299 ng / ml and transferransfine saturation < 20%) People who have discontinued the Warfarin at least 72 hours before surgery. People who have discontinued the anti-platelet at least drugs 3-5 days bofore sugery. 18 years no limit Both Elimination of patients with liver disorders Elimination of patients with inherited and well-known coagulation disorders Elimination Emergency sugeries Elimination pregnant women Redo surgery D50.9 Iron deficiency anaemia, unspecified Treatment - Drugs Other Iron sucrose group:Patients in this group receive 1000 mg of an Iron sucrose drug by injection and within 3 weeks of surgery. Ferric carboxymaltose group: Patients in this group receive 1000 mg of Ferricarboxymaltose by injection and within 3 weeks of surgery. 1) Amount of ferritin changes in 2 groups studied. Timepoint: Before surgery and 3 days after surgery. Method of measurement: Ferritin Test. 2)Amount of Hb changes l in 2 groups studied. Timepoint: Before surgery and 3 days after surgery. Method of measurement: CBC Test. 1) frequency of patients who transfused. Timepoint: 7 days after surgery. Method of measurement: Check patient records for the number of blood units consumed. 2) Average number of blood units consumed. Timepoint: 7 days after surgery. Method of measurement: Check patient records for the number of blood units consumed. Blood Transfusion Center Tabriz University of Medical Sciences Blood Transfusion Center Approved 2018-06-26 Ethics committee of Tabriz University of Medical Sciences Golgasht Ave,Azadi Blvd,Oloom pezeshki Tabriz Tabriz East Azarbaijan Iran (Islamic Republic of)