IRCT20141124020071N4 IRCT 2019-01-26 Kermanshah University of Medical Sciences The efficacy of Dorema ammoniacum D. Don oleo-gum-resin on chloasma Formulationand evaluation of the efficacy of topicalpreparation from Dorema ammoniacum D. Don oleo-gum-resin in patients with chloasma 2018-10-06 anticipated 60 Complete https://irct.ir/trial/33873 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Topical formulation of Dorema ammoniacum D.Don will give to the patients that chose based on the Block randomized method and divided into two groups including case and control group, Blinding description: Patients and the person who provides the drug to patients will be unaware of the drug content. N/A chloasma. Intervention 1: Intervention group: use of 1 grams topicalpreparation from Dorema ammoniacum D. Don oleo-gum-resin twice daily for 1 month. Intervention 2: Control group: use of 1 grams Eucerine Cream twice daily for 1 month. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no information.