]>
IRCT20100223003408N4 IRCT 2018-12-03 Shiraz University of Medical Sciences The effect of angostifolia in patients with Cirrhosis The effect of adding angostifolia powder in addition to conventional medical treatment of liver cirrhosis on Levels of inflammatory markers in plasma and liver enzymes 2018-06-22 anticipated 48 Complete https://irct.ir/trial/33839 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization, Individual, Random allocation software, 12 randomization sequence in permuted blocks of size 4 In this study, the allocation of people to the two groups was done using permutational block method. In this method, A represents the person who receives the intervention, and B represents the person who is in the control group. Considering the quadruple block; reversing the AABB code 0, replacing the ABAB code 1, the ABBA code 2, the BAAB code 3, the BBAA code 4, and the BABA code 5 to 9. Then, using the random number table, we select the starting point randomly, followed by 12 rows or columns. Given the order of the numbers of the table, we chime each corresponding number to the number we encountered, for example, if the 3 first digits of the random number table are 1, 0, and 5, respectively. The order of receiving treatment by the first 12 people in both groups will be ABABAABBBABA left to right, respectively. So, finally, by selecting 12 tables from the table, how all 48 people will be assigned will be identified in two groups. 3 Liver cirrhosis. Intervention 1: Control group : 15gr corn starch with 1glass water daily for 10 weeks in addition to conventional medical treatment of liver cirrhosis. Intervention 2: Intervention group :15gr angostifolia powder with 1 glass water daily for 10 weeks in addition to conventional medical treatment of liver cirrhosis. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Maryam Ekramzadeh
Razi Blvd
Shiraz Iran (Islamic Republic of) 71536-75541 +98 71 3725 1001 Ekramzadeh@sums.ac.ir Shiraz University of Medical Sciences scientific Maryam Ekramzadeh
Razi Blvd
Shiraz Iran (Islamic Republic of) 71536-75541 +98 71 3725 1001 Ekramzadeh@sums.ac.ir Shiraz University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Person with Cirrhosis Age between 18 to 60 years 18 years 60 years Both Diabetes Hypothyroidism or hyperthyroidism Kidney disease Lung disease Cardiovascular disease Smoking Alcohol and tobacco consumption K74.6 Other and unspecified cirrhosis of liver Treatment - Drugs Treatment - Drugs Control group : 15gr corn starch with 1glass water daily for 10 weeks in addition to conventional medical treatment of liver cirrhosis Intervention group :15gr angostifolia powder with 1 glass water daily for 10 weeks in addition to conventional medical treatment of liver cirrhosis Tumor necrosis factor-alpha. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: ELISA. Alanine aminotransferase. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: ALT Kit. Aspartate transaminase. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: AST Kit. Shiraz University of Medical Sciences Approved 2018-06-15 Shiraz University of Medical Sciences Zand street Shiraz Fars Iran (Islamic Republic of)