]>
IRCT201306083289N6 IRCT 2014-01-17 Arak University of Medical Sciences,Vice Chancellor for Research Comparison of isoflurane and sevoflurane in nasal surgeries Comparison of bleeding during anesthesia with isoflurane and sevoflurane in endoscopic nasal surgeries and tympanomastoidectomy 2012-12-21 anticipated 90 Complete https://irct.ir/trial/3361 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: ninety patients candidate for nasal endoscopic surgeries and tympanoplasty divided into two equal groups using a randomized block. 2 Bleeding. Intervention 1: Intervention 1: Inhalational Sevoflurane, chemical composition 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane, marketed by Abbot Park, North Chicago, Illinois, which is used by 1 MAC, peri-operative. Intervention 2: Intervention 2: Inhalational Isoflurane, chemical composition 1-chloro-2,2,2-trifluoromethyl ether, marketed by Nicholas Piramal(I)London, which is used by 1 MAC, peri-operative.
public Dr Esmaeil Moshiri
Arak University of Medical Sciences. Basij Square. Sardasht. Arak. Iran
Arak Iran (Islamic Republic of) +98 86 1417 3641 dr_moshiri@arakmu.ac.ir Arak University of Medical Sciences scientific Dr Esmaeil Moshiri
Arak University of Medical Sciences. Basij Square. Sardasht. Arak. Iran
Arak Iran (Islamic Republic of) +98 86 1417 3641 dr_moshiri@arakmu.ac.ir Arak University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: All the patients who underwent endoscopic sinus surgery or tympanomastoidectomy Exclusion criteria: 1. Age over 55 years 2. Patients with history of cardiovascular problems, hypertension, and COPD 3. Patients under anticoagulation treatment 4. Using tranquilizers 5. Patients with drug abuse 18 years 55 years Both Y60.0 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care( During surgical operation) Treatment - Other Treatment - Other Intervention 1: Inhalational Sevoflurane, chemical composition 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane, marketed by Abbot Park, North Chicago, Illinois, which is used by 1 MAC, peri-operative. Intervention 2: Inhalational Isoflurane, chemical composition 1-chloro-2,2,2-trifluoromethyl ether, marketed by Nicholas Piramal(I)London, which is used by 1 MAC, peri-operative. Bleeding. Timepoint: In the end of surgery. Method of measurement: Quality grading that is recorded in patient's sheet. Blood pressure. Timepoint: At the beginning of operation and every 15 minutes during surgery. Method of measurement: Measure with mercury sphygmomanometer and record in patient's sheet. Heart rate. Timepoint: At the beginning of operation and every 15 minutes during surgery. Method of measurement: The number of heart beats per minute is calculated and recorded in the patient's sheet. Arterial saturation of oxygen. Timepoint: At the beginning of operation and every 15 minutes during surgery. Method of measurement: Measure with pulse oximeter and record in patient's sheet. Arak University of Medical Sciences,Vice Chancellor for Research Approved 2012-12-03 Ethics committee of Arak University of Medical Sciences Arak University of Medical Sciences. Basij Square. Sardasht. Arak. Iran Arak Iran (Islamic Republic of)