IRCT20100107003014N21 IRCT 2018-12-06 Mazandaran University of Medical Sciences Effect of hydroalcoholic extract of Ruscus hyrcanus in treatment of chronic venous insufficiency Study of therapeutic effects of ointment containing hydro alcoholic extract of root and rhizome of Ruscus hyrcanus woronow in patients with chronic venous insufficiency (Varicos vein); a randomized, double blind, controlled with placebo. 2018-09-23 anticipated 60 Complete https://irct.ir/trial/32918 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization by a random number table, Blinding description: Ointments made in "placebo" and "Drug" groups, are numbered in the list by the supervisor. After prescribing by the physician, the code of prescribed ointment will be entered into the questionnaire. Physician, Patient and investigator are not aware of the type of ointment. 0 (exploratory trials) Varicose vein of lower extremities. Intervention 1: Intervention group: Ruscus extract 2% ointment/ 2 times daily/ 1 cm of the ointment/ For one month. Intervention 2: Control group: ointment formolation without any drugs/ 1 cm of the ointment/ For one month. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is not any more information