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IRCT20180711040425N1 IRCT 2018-10-10 Shahroud University of Technology The effect of exercise intensity and supplementation on diabetes The effect of 4 weeks high-intensity interval training (HIIT) with Spirulina supplementation on serum total antioxidant capacity (TAC) and Malondialdehyde (MDA) in women with type 2 diabetes (T2D) 2018-07-23 anticipated 60 Complete https://irct.ir/trial/32893 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Factorial, Purpose: Basic scienece, Randomization description: To allocate participants to research groups, a computer inventory of random numbers using a computer software (Random Allocation Software 2.0) will first be created by one of the research colleagues.Allocate participants by one of the research team members that is not related to the participants is done by block randomization with 4 blocks within the experimental (training) and control groups. Participants will be classified into 4 groups using randomized block method, depending on their blood glucose variables. The limitation of this method is the prediction of final allocation, which is the solution of random use of blocks of different sizes. Assignment sequences are hidden by the envelopes encoded in the order numbered, and the letter envelopes are opened only after all the initial and initial evaluations of the participants have been made. N/A Type 2 diabetes. Intervention 1: first Intervention group: The training group consisted of three sessions per week of high intensity interval training for 4 weeks. Training sessions consisted of 45 minutes walk or running on a treadmill. Each session is divided into 10 minutes of warming up with an intensity 50-70% HRR, 10 minutes of cooling down with an intensity 50-70% HRR and 25 minutes of high intensity interval training ( HIIT The training section consists of 4 4-minute sections, with an intensity of 85 to 95% HRR and 3-minute rest periods, with an intensity of 50-70% HRR). Intervention 2: Spirulina 2 grams daily, including 4 pills 500 mg before meals, for 4 weeks. This supplement is made by Qeshm algae and contains spirulina pure green algae. spirulina is a blue-green wonder aglae. It is the most powerful food existing in nature with 60% protein content and 18 amino acids. Intervention 3: Third intervention group: Exercise + supplement group consisting of three sessions per week of high intensity interval training for 4 weeks and 2 grams of supplementation of spirulina per day for 4 weeks. Intervention 4: fourth intervention group: control group, No Spirulina supplement and no exercise. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information.
public saeedeh khodadadi
Shahroud Industrial University, Haft-e Tir Square
Shahrood Iran (Islamic Republic of) 3619995161 +98 23 3239 2204 ss.kk1159@yahoo.com Shahroud University of Technology scientific Saeedeh Khodadadi
Shahrood
Shahrood Iran (Islamic Republic of) 3619995161 +98 23 3239 2204 ss.kk1159@yahoo.com Shahrood university of technology Iran (Islamic Republic of) T2D detection < 10 years ago Ages 40 to 65 years old No dependency to insulin The use of commonly used diabetes medications, such as metformin and glenalbelamine 40 years 65 years Female Cardiovascular disease Coronary artery disease Atrial fibrillation High blood pressure Congenital heart disease Retinopathy Neuropathy Body mass index 35 Ischemia in echocardiography Disability that causes difficulty in practice. E11 Type 2 diabetes mellitus Other Other Other Other first Intervention group: The training group consisted of three sessions per week of high intensity interval training for 4 weeks. Training sessions consisted of 45 minutes walk or running on a treadmill. Each session is divided into 10 minutes of warming up with an intensity 50-70% HRR, 10 minutes of cooling down with an intensity 50-70% HRR and 25 minutes of high intensity interval training ( HIIT The training section consists of 4 4-minute sections, with an intensity of 85 to 95% HRR and 3-minute rest periods, with an intensity of 50-70% HRR). Spirulina 2 grams daily, including 4 pills 500 mg before meals, for 4 weeks. This supplement is made by Qeshm algae and contains spirulina pure green algae. spirulina is a blue-green wonder aglae. It is the most powerful food existing in nature with 60% protein content and 18 amino acids. Third intervention group: Exercise + supplement group consisting of three sessions per week of high intensity interval training for 4 weeks and 2 grams of supplementation of spirulina per day for 4 weeks fourth intervention group: control group, No Spirulina supplement and no exercise Serum levels of Malondialdehyde in women with type 2 diabetes. Timepoint: One day before the session begins and 48 hours after the end of the exercise. Method of measurement: The MDA level measurement will be performed by ELISA, using a commercially available chemical calorimetry laboratory kit (MDA test kit; ZellBio GmbH, Ulm, Germany). Serum Total Antioxidant Capacity in women with type 2 diabetes. Timepoint: One day before the session begins and 48 hours after the end of the exercise. Method of measurement: The serum level of antioxidant total capacity will be measured by ELISA and using a commercial kit under the manufacturer's protocols (ZellBio GmbH, Germany). Shahroud University of Technology Approved 2018-07-02 Ethics Committee on Biomedical Research of Shahroud University of Medical Sciences. Shahrood University of Technology, Haft-e-Tir Square shahrood Semnan Iran (Islamic Republic of)