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IRCT20180712040438N1 IRCT 2018-08-11 Tabriz University of Medical Sciences Effect of vitamin C supplementation on cardiovascular bio markers in patients undergoing open heart surgery The effect of vitamin C supplement on the level of CK-MB and Troponine enzymes in patients undergoing Coronary Artery Bypass Graft (CABG) surgery 2018-07-23 anticipated 80 Complete https://irct.ir/trial/32632 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The eligible participants will be randomly allocated to intervention and placebo groups using a software generated random permuted blocks. The generated random sequence will be kept in a protected location and administered by an independent third party who is blind to the trial throughout the study, Blinding description: In this double-blind study, no patient and investigator will be aware of the treatment assignments for the duration of the study. For blinding the trial, the tablet and placebo, will be identical in appearance, packaging, and labeling. All capsules will be packed and encoded by the company (Darou Pakhsh Company). 2-3 سکته‌ قلبی. Intervention 1: Intervention group: Patients in this group will receive Vitamin C for 7 days. (a product by darou pakhsh Co. and made in The Iran) and used twice a day. Intervention 2: Control group: Patients in this group will receive maltodextrin tablet for 7 days which are same size and shape ( product by darou pakhsh Co. and made in The Iran) and used twice day. Yes - There is a plan to make this available What will be shared: Data collected for the primary outcomes will be shared. When: Accessibility to data is possible 8 months after publication. To whom: The data will only be available for people working in academic institutions. Conditions: The data of the present study will only be accessible by other researchers, for conducting Meta analysis. Where to obtain: Jalal Moludi, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, +989399516760, jmoludi@yahoo.com How to obtain: The applicator can send a request to the person responsible for the study by email and within 10 days the document will be sent to the requesting person. Comments:
public Jalal Moludi
Golgasht St
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 2148 moludij@tbzmed.ac.ir Tabriz University of Medical Sciences scientific Jalal Moludi
Golgasht St
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 2148 moludij@tbzmed.ac.ir Tabriz University of Medical Sciences Iran (Islamic Republic of) 80 patients' eligible for CABG surgery no limit no limit Both Recent intake of antioxidants or warfarin Valve replacement subjects with body mass index (BMI) above 30 Kidney disease (creatinine above 1.5) I21 ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction Treatment - Drugs Placebo Intervention group: Patients in this group will receive Vitamin C for 7 days. (a product by darou pakhsh Co. and made in The Iran) and used twice a day. Control group: Patients in this group will receive maltodextrin tablet for 7 days which are same size and shape ( product by darou pakhsh Co. and made in The Iran) and used twice day. Level of Troponin. Timepoint: Baseline and 7 days after intervention. Method of measurement: via ELISA kit. Level of CK-MB. Timepoint: Baseline and 7 days after intervention. Method of measurement: via ELISA kit. Tabriz University of Medical Sciences Approved 2018-01-27 ﮐﻤﯿﺘﻪ اﺧﻼق داﻧﺸﮕﺎه ﻋﻠﻮم ﭘﺰﺷﮑﯽ و ﺧﺪﻣﺎت درﻣﺎﻧﯽ ﺗﺒﺮﯾﺰ Tabriz University of Medical Sciences, Attar Neyshabouri Av., Golgasht St. Tabriz East Azarbaijan Iran (Islamic Republic of)