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IRCT20150902023855N3 IRCT 2020-07-14 Semnan University of Medical Sciences Comparison between the clinical efficacy of Intravenous Fentanyl and Ketorolac in relieving renal colic pain Comparison between the clinical efficacy of Intravenous Fentanyl and Ketorolac in relieving renal colic pain 2020-06-03 anticipated 110 Complete https://irct.ir/trial/31789 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be examined after obtaining a diagnosis and demographic information. Eligible patients entering the study are randomly divided into two groups by permuted balanced block randomization. And the randomization list will be prepared using block stratified randomization software for windows version 6, Blinding description: The study is designed as single blind and only patients were blind in this study. 2-3 Acute Renal Colic. Intervention 1: Intervention group 1: patients will receive 0.1mg intravenous Fentanyl (Darou Pakhsh Pharmaceutical company) infused in 100 ml normal saline within 10 minutes. Intervention 2: Intervention group 2: patients will receive 30mg intravenous Ketorolac(Alborz Darou Pharmaceutical company) within 15 seconds.
public Dr Davood Arab
Kosar Hospital, Bassij Blvd., Semnan
Semnan Iran (Islamic Republic of) 3519899951 +98 23 3343 7830 drdavoodarab@semums.ac.ir Semnan University of Medical Sciences scientific Dr Davood Arab
Kosar Hospital, Bassij Blvd., Semnan
Semnan Iran (Islamic Republic of) 3519899951 +98 23 3343 7830 drdavoodarab@semums.ac.ir Semnan University of Medical Sciences Iran (Islamic Republic of) Patients with a history of unilateral abdominal or flank pain that the treating emergency physicians suspect to be renal colic Ultrasonography or CT Scan or intravenous pyelography (IVP) findings consistent with the diagnosis of renal stone Stone excretion 18 years 55 years Both Visual Analog Scale (VAS)≤3 History of peptic ulcer disease History of asthma History of bleeding disorder Using of oral anticoagulant Impaired renal or hepatic function Hypersensitivity to Aspirin or NSAID or Fentanyl Pregnant and breast-feeding women Received Sedative,Antipsychotic,MAO-I, painkillers within 6 hours before Younger than 18 and greater than 55 years old Calculus o N20.2 Treatment - Drugs Treatment - Drugs Intervention group 1: patients will receive 0.1mg intravenous Fentanyl (Darou Pakhsh Pharmaceutical company) infused in 100 ml normal saline within 10 minutes. Intervention group 2: patients will receive 30mg intravenous Ketorolac(Alborz Darou Pharmaceutical company) within 15 seconds. Pain level. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Visual Analogue Scale. Heart rate. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Radial puls. Blood pressure. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Sphygmomanometer. Body temperature. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Thermometer(axillary). Respiratory rate. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Physical exam. Fentanyl side effects. Timepoint: In all the time in care. Method of measurement: Questionnaire and physical examination. Ketorolac side effect. Timepoint: In all the time in care. Method of measurement: Questionnaire and physical examination. Semnan University of Medical Sciences Approved 2020-06-02 Ethics committee of Semnan University of Medical Sciences Kosar Hospital,Bassije Blvd,Semnan,Iran Semnan Semnan Iran (Islamic Republic of)