IRCT20141009019470N86 IRCT 2019-08-26 Shiraz University of Medical Sciences The effect of nebulization on incidence and severity of sore throat after general anesthesia. Comparison of pre-anesthesia and pre-intubation prescription of nebulized magnesium sulfate and dexamethasone on the incidence and severity of post extubation sore throat in patients under general anesthesia. 2019-09-06 anticipated 300 Complete https://irct.ir/trial/31253 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients will be randomly assigned to one of the three groups based on a table which is derived from randomization.com site and the study will be started, Blinding description: The patient and the person who is involved in the preparation of the Nebulizers, as well as the person responsible for data collection are not aware of the type of intervention receiving by each study group. 2-3 post extubation sore throat. Intervention 1: Intervention group: The intervention group A consists of patients receiving 10 mg 8 mg dexamethasone nebuliser in 100 ml of normal saline for 5 minutes before the induction. Intervention 2: Intervention group: The intervention group B consists of patients who receive magnesium sulfate nebulizer (30 mg per kg body weight) in 100 ml of normal saline for 10 minutes before the induction. Intervention 3: Control group: Patients in the C group will receive normal saline for five minutes before the induction. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Its against our policies.