]>
IRCT20160821029446N5 IRCT 2018-06-20 Tehran University of Medical Sciences Comparative of the Effectiveness of Turmeric Extract with Mefenamic Acid on Pain Intensity of Primary Dysmenorrhea Comparative of the Effectiveness of Turmeric Extract with Mefenamic Acid on Pain Intensity of Primary Dysmenorrhea 2018-06-22 anticipated 132 Complete https://irct.ir/trial/31012 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The sampling method will be stratified quota sampling in which each dormitory will be considered as a stratify. After selecting the samples from the first dormitory, they were randomly divided into two groups receiving Mefenamic acid capsules and turmeric extract capsules. The samples were selected randomly in the second dormitory like those of the first one, Blinding description: A double-blind randomized clinical trial is conducted. The study is blinded by coding the drugs by the pharmacist (A and B), and the pharmacist placed the provided drugs (i.e. mefenamic acid and turmeric extract capsules) in the cans with the same colors and shapes and randomly coded them. Three capsules should be taken for three days in a month during three months and the researcher and participants do not have any idea about which drug is coded as A or B. For each half of the participants in the dormitory, codes are written on the pieces of the paper and then are placed in a bag. At the beginning of the treatment cycle, the participants were asked to take a code from the bag by chance and then they were given a drug according to the selected code. 3 Dysmenorrhea. Intervention 1: Intervention group: Every participant will be randomly given 27 turmeric capsules for three consecutive cycles. After explaining how each drug is taken, (i.e. three capsules should be taken in the duration of 8 hours from the first day of menstrual period for three days), they will be asked to complete the forms after taking the drug. Intervention 2: Control group: Every participant will be randomly given 27 Mefenamic acid capsules for three consecutive cycles. After explaining how each drug is taken, (i.e. three capsules should be taken in the duration of 8 hours from the first day of menstrual period for three days), they will be asked to complete the forms after taking the drug. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public Maryam Yazdi
Iran, Tehran, Tohid Square, Tehran University of Medical Sciences, Faculty of Nursing and Midwifery
Tehran Iran (Islamic Republic of) 1419733171 +98 21 2966 1717 yazdimaryam20@yahoo.com Tehran University of Medical Sciences scientific Maryam Damghanian
Iran, Tehran, Tohid Square, Tehran University of Medical Sciences, Faculty of Nursing and Midwifery
Tehran Iran (Islamic Republic of) 1419733172 +98 21 6692 7171 Maryam_damghanian@yahoo.com Tehran University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Being single Aged between 18-28 At least one semester has been left Having dysmenorrhea with the features of primary dysmenorrhea in most menstrual cycles in the last 6 months Having regular menstrual cycle (21-35 days) Not having female genital problems (ovarian cysts, fibroma, abnormal uterine bleeding) Absence of coagulation disorders Absence of abdominal and pelvic surgery history Absence of drug interaction such as glycemic control drugs and high blood pressure drugs Absence of allergy to turmeric and its compounds Absence of allergy to non-steroidal anti-inflammatory drugs Not using relaxation techniques over the last 6 months Absence of physical and mental illness Not participating in other studies 18 years 28 years Female Unwillingness to continue the participation during the study for any reason Getting married during the study any Unmodified side effects N94.4 Primary dysmenorrhea Treatment - Drugs Treatment - Drugs Intervention group: Every participant will be randomly given 27 turmeric capsules for three consecutive cycles. After explaining how each drug is taken, (i.e. three capsules should be taken in the duration of 8 hours from the first day of menstrual period for three days), they will be asked to complete the forms after taking the drug. Control group: Every participant will be randomly given 27 Mefenamic acid capsules for three consecutive cycles. After explaining how each drug is taken, (i.e. three capsules should be taken in the duration of 8 hours from the first day of menstrual period for three days), they will be asked to complete the forms after taking the drug. Dysmenorrhea intensity. Timepoint: In 2 control cycles and then after taking drugs In the form of three capsules every 8 hours for three days until 3 cycles. Method of measurement: verbal multidimensional scoring system. Blood loss during menstrual cycle. Timepoint: In 2 control cycles and then after taking drugs In the form of three capsules every 8 hours for three days until 3 cycles. Method of measurement: Pictorial Blood Loss Assessment. Tehran University of Medical Sciences Approved 2018-04-08 Ethics Committee of Nursing and Midwifery and Rehabilitation Faculty of Tehran University of Medical Nursing and Midwifery Faculty of Tehran University of Medical Sciences, Tohid Square, Tehran Tehran Tehran Iran (Islamic Republic of)