]>
IRCT20100829004655N10 IRCT 2018-09-17 Kashan University of Medical Sciences Effect of pomegranate seed extract on the improvement of stomatitis Pomeggranate seed extract and stomatitis The effect of mouth wash pomegranate seed extracts on improving oral mucositis in patients treated with chemotherapy 2018-09-23 anticipated 70 Complete https://irct.ir/trial/30938 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: In this study, the following people were blind and did not know of the content two glass: 1) the person who gave the glass to the patients and examine the patients' oral mucosa 2) patients, Randomization description: Cancer patients who are continually referred to randomly assigned block randomization based on a computer spss program will be divided into two groups: intervention and control, Blinding description: Patients have no information about the kind of consultation that receive. N/A Stomatitis. Intervention 1: The intervantion group use solution of routine + Pomegranate seed extract, each 100 cc containing lidocaine 2%, 50 mg (2.5.2 cc), 6 cc nystatin drop, Al-mg-s syrup 27.5 cc, Diphenhydramine 14 cc and 50 cc syrup of extract Pomegranate seed (50 to 50%) 4 times a day, for 14 days after breakfast, lunch, dinner, and before bed, 15 cc each time and keep it for 3 minutes, then These patients should not wash their mouths and give them an hour to eat food. Considering the two-sidedness of the study, oral mucosa on the first, seventh and fourteenth days by a nurse trained in the ancology department who does not lnow the mouthwash solution and then checklist is completed . Intervention 2: Control group: Routine mouthwash (lidocaine 2% 100 mg (5 cc), 12 cc nystatin drop, AL-mg-s 55 cc, diphenhydramine syrup 28 cc) 4 times a day, for 14 days after breakfast, lunch, Dinner, and before bed, 15 cc each time and keep it for 3 minutes. Then they should be discarded. These patients should not wash their mouths and give them up to one hour of food intake, and according to double-blind In the study, the oral mucosa on the first, seventh and fourteenth days is checked by the nurse in the oncology nurse who is unaware of the type of mouthwash and the checklist is completed. Yes - There is a plan to make this available What will be shared: The total potential data can be shared after unidentifiable people When: Start the access period 6 months after printing the results To whom: Only available to scholars working in academia and academia Conditions: If you observe trust and mention the source, the data can be used by researchers Where to obtain: Send the following e-mail to the following address: taghadosi_m@Kaums.ac.ir How to obtain: After receiving the letter via email, your request will be reviewed within 2 weeks, and the data will be sent to the applicant at the discretion. Comments:
public Mohsen Taghadosi
Arctic Blvd Ravandi, Kashan Universitr of Medical Sciences
kashan Iran (Islamic Republic of) 87159/81151 +98 31 5554 0021 taghadosi_m@Kaums.ac.ir Kashan University of Medical Sciences scientific Mohsen Taghadosi
Arctic Blvd Ravandi , Kashan University of Medical Sciences
Kashan Iran (Islamic Republic of) 87159/81151 +98 31 5554 0021 taghadosi_m@Kaums.ac.ir Kashan University of Medical Sciences Iran (Islamic Republic of) Undergoing chemotherapy Having consciousness Age above 18 years old Satisfaction with participation in the study Non-allergenic to herbal products 18 years 80 years Both Getting radiotherapy during research Fever Use of other mouthwashes other than mouthwashes defined in this study The patient's decision to withdraw from the study k12.1 Stomatitis Treatment - Drugs Treatment - Drugs The intervantion group use solution of routine + Pomegranate seed extract, each 100 cc containing lidocaine 2%, 50 mg (2.5.2 cc), 6 cc nystatin drop, Al-mg-s syrup 27.5 cc, Diphenhydramine 14 cc and 50 cc syrup of extract Pomegranate seed (50 to 50%) 4 times a day, for 14 days after breakfast, lunch, dinner, and before bed, 15 cc each time and keep it for 3 minutes, then These patients should not wash their mouths and give them an hour to eat food. Considering the two-sidedness of the study, oral mucosa on the first, seventh and fourteenth days by a nurse trained in the ancology department who does not lnow the mouthwash solution and then checklist is completed . Control group: Routine mouthwash (lidocaine 2% 100 mg (5 cc), 12 cc nystatin drop, AL-mg-s 55 cc, diphenhydramine syrup 28 cc) 4 times a day, for 14 days after breakfast, lunch, Dinner, and before bed, 15 cc each time and keep it for 3 minutes. Then they should be discarded. These patients should not wash their mouths and give them up to one hour of food intake, and according to double-blind In the study, the oral mucosa on the first, seventh and fourteenth days is checked by the nurse in the oncology nurse who is unaware of the type of mouthwash and the checklist is completed. Stomatitis. Timepoint: Before intervention, days 1, 7 and 14 after intervention. Method of measurement: Standardized checklist stomatitis WHO. Change grade of stomatitis. Timepoint: Before intervention, days 1, 7 and 14 after intervention. Method of measurement: Standardized checklist stomatitis WHO. Kashan University of Medical Sciences Approved 2018-07-30 Ethics committee of Kashan University of Medical Sciences kashan University of Medical Sciences , Km 5 ghotb Radvandi Blvd. Kashan Isfehan Iran (Islamic Republic of)