IRCT20180501039490N1 IRCT 2018-06-06 Mashhad University of Medical Sciences Comparing the effect of Centella Asiatica and Conjugated estrogen vaginal cream for the treatment of vaginal atrophy in postmenopausal women Comparing the effect of Centella Asiatica and Conjugated estrogen vaginal cream for the treatment of vaginal atrophy in postmenopausal women 2018-05-22 anticipated 64 Complete https://irct.ir/trial/30888 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The random allocation will be done by typing on the code assigned to the Centella Asiatica cream and the conjugated estrogen cream. These codes are wrriten on two peaces of papers which are place in one box. At the first day of sampling, the researcher takes one of the papers inside the box , which will be assigned to the first sample,and the other code will be allocated to the next sample(control). In this way, subjects will be assigned to intervention and control group, Blinding description: Similarity of creams in terms of shape, color and size of cream-containing shells. 4 Vaginal Atrophy. Intervention 1: Intervention group: Centlla Asiatica Cream 1% , daily for 8 weeks as an applicator, produced in the laboratory of school of Pharmacy, Mashhad University of Medical Sciences, Mashhad,Iran. Intervention 2: Control group: Conjucated estrogen cream. No - There is not a plan to make this available Justification or reason for not sharing IPD is "No more information"