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IRCT20180305038966N1 IRCT 2018-03-29 Kashani Hospital Study of the Effect of bread containing flaxseed on serum level of Apelin and lipid profile in hyperlipidemic patients Study of the Effect of bread containing flaxseed on serum level of Apelin and lipid profile in hyperlipidemic patients 2018-01-28 anticipated 48 Complete https://irct.ir/trial/29989 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: 48 patients are randomly assigned to two equal groups (lottery) of intervention and placebo, Blinding description: Researchers and patients are unaware of the type of bread they are being divided. N/A Hyperlipidemia. Intervention 1: Intervention group: intake 2 unit of bread containing 20 gram of flax seed flour and 80 gram of wheat flour for 6 weeks and twice a day. Intervention 2: Control group: intake 2 unit of simple bread containing 100 gram of wheat flour for 6 weeks and twice a day. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is I will not be able to make decisions about the details of the publication at the beginning
public Nahid Shakeri
Shahid Hesarak B lvd , University square
Tehran Iran (Islamic Republic of) 1477893855 +98 21 4486 1815 nutrition@mail.mui.ac.ir Islamic Azad University scientific Mohammad Hasan Entezari
Hezarjarib Ave, Isfahan University of MedicalSciences
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3792 2775 entezari@hlth.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) high is one of the lipid factors: cholesterol is grater than or equal to 200.triglycerides grater or equal. LDL is grater or equal 130 and rate of HDL is less than 40 for men and 50 mg per deciliter for women(high levels of LDL or cholesterol are essential Men and wemen 20-50 years old Patients who agree to participate in the study 20 years 50 years Both Tobacco use Adherence to a particular diet Consumption bread of flaxseed in the last 6 months Pregnancy, breast feeding, menopause E78 Disorders of lipoprotein metabolism and other lipidemias Prevention Placebo Intervention group: intake 2 unit of bread containing 20 gram of flax seed flour and 80 gram of wheat flour for 6 weeks and twice a day Control group: intake 2 unit of simple bread containing 100 gram of wheat flour for 6 weeks and twice a day Serum level of LDL. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl. Serum level of total cholesterol. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl. Serum level of Apelin. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Eliza_ picogram/ml. Serum level of triglyceride. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl. Serum level of HDL. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl. Blood pressure. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Digital Manometer mmHg. Body mass index. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Formula weight/High2. Physical activity. Timepoint: Initially, the middle and end of the sixth week study. Method of measurement: Met questionnaire. Food intake. Timepoint: Initially, the middle and end of the sixth week study. Method of measurement: Food frequency questionnaire 3 days. Waist. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Strip Meter- centimeters. Kashani Hospital Approved 2018-02-19 Ethics committee of Science and Research Tehran Shahid hesarak Bivd, university Square Tehran Tehran Iran (Islamic Republic of)