IRCT20180203038599N1 IRCT 2018-03-26 Ahvaz University of Medical Sciences Comparison of the Efficacy of Intradermal injected Tranexamic Acid vs Hydroquinone cream in the Treatment of Melasma AMS Comparison of the Efficacy of Intradermal injected Tranexamic Acid vs Hydroquinone cream in the Treatment of Melasma 2017-08-23 anticipated 40 Complete https://irct.ir/trial/29822 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: -, Randomization description: Permuted 4 block randomization, Blinding description: Value assessment blind about 4 and 10 mg/ml tranexamic acid dose. 2 Melasma. Intervention 1: Intervention group 1: Right side face treated with intradermal 4 mg/ml tranexamic acid every other week for 12 weeks. Intervention 2: Intervention group 2: Right side face treated with intradermal 10 mg/ml tranexamic acid every other week for 12 weeks. Tranexamic acid is a product of Caspian Tamin Pharmaceutical Company in 500 mg/5ml vial. Intervention 3: Control group: Left side face treated with eldoquin fort 4% cream is a product of ICN company twice a day for 12 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.