IRCT20180206038645N1 IRCT 2018-03-05 Zanjan University of Medical Sciences Rheum palmatum root in systolic heart failure Clinical trial of the effect of "Rheum palmatum root"on quality of life in patients with systolic heart failure 2018-04-04 anticipated 60 Complete https://irct.ir/trial/29597 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: By using random numbers table patiends are divided in two 30 person case_control groups, Blinding description: All participations and researchers are blind in this study, coding of medicine and placebo are under the responsibility of a statistical adviser who is not blind. 3 Systolic heart failure. Intervention 1: Intervention group: Dry extract of Rheum palmatum root with a concentration of 10% relative to 100 gr of roots of the plant, has been standardized 250mg per capsule at the school of pharmacy of Shahid Behest university of Medical Sciences.The drug is given one capsule every 12 hours for 60 days to volunteer patients with heart failure who have ejection fraction equal to or less than 40%. Intervention 2: Control group: Placebo in the control group contains starch corn which is provided in capsules and boxes of the same intervention group at the school of Pharmacy of Shahid Behest university of Medical Sciences.The placebo is given one capsule every 12 hours for 60 days to volunteer patients with heart failure who have ejection fraction equal to or less than40%. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is THe way of publishing is not known.