IRCT20180129038549N2 IRCT 2018-02-20 Esfahan University of Medical Sciences Effect of topical ketamine on pain relief Comparison of the effectiveness of lidocaine-perilocaine cream with topical ketamine in reducing local pain in patients 2017-10-23 anticipated 75 Complete https://irct.ir/trial/29316 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomly using computer software, Blinding description: Ketamine ointment is prepared by a pharmacist and the same is packed with EMLA ointment, and then numbered and given to the nurse. The nurse and the physician and patient do not know the ointment content. 3 ... Intervention 1: Patients are treated with EMLA cream. A 5%EMLA cream is a combination of 2.5% lidocaine and 2.5% perlocaine produced by Iranian chemistry company Iran. For each patient, 2 grams of 4 × 2.5 cm spam cream are applied and then covered with gas.Intervention group:. Intervention 2: Intervention group: Patients treated with topical ketamine (vial 10 ml ketamine hydrochloride 50 mg / ml for i.m / i.v, TRITTAU made in Germany) are treated. To this end, we mixed the injection of 2cc ketamine with 10cc cold cream. Each cc of ketamine contains 50 mg. The solution thus obtained will have a concentration of 10 mg per cubic centimeter. Then, for each patient, we cover a cc of the solution made at the place to be taken and used for gas. Intervention 3: Control group: placebo. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information