IRCT20090912002445N6 IRCT 2018-01-22 Shiraz University of Medical Sciences Effects of Ondansetron and Clonazepam on Nausea and Vomiting after Laparoscopic Cholecystectomy Effects of Preoperative Ondansetron and Clonazepam on Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy; A Randomized Double-Blind, Placebo Controlled Trial 2018-01-21 anticipated 90 Complete https://irct.ir/trial/28871 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The included patients were randomly assigned to 3 study groups using a computer-based random digit generator utilizing the admission numbers, Blinding description: All the patients and physicians administrating the medications will blinded toward the intervention. 1-2 Laparoscopic cholecystectomy. Intervention 1: Intervention group: 2 mg of oral clonazepam (Sobhan Darou Inc., rasht, Iran) and intravenous injection of placebo 15-minute prior to induction of anesthesia. Intervention 2: Intervention group: 4 mg intravenous injection of ondansetron (Alborz Darou Inc, Tehran, Iran) and oral tablets of placebo. Intervention 3: Control group: oral and intravenous injection of placebo. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is -