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IRCT20171225038058N1 IRCT 2018-03-09 Kurdistan University of Medical Sciences Compare the effect of Matricaria CHamomile capsule and Achillea Millefolium capsule on menestural pain. Comparative study on the effect of Matricaria CHamomile capsule and Achillea Millefolium capsule on primary dysmenorrhea intensity in university students. 2018-05-21 anticipated 60 Complete https://irct.ir/trial/28417 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: -, Randomization description: Initialy one month before taking CHamomile capsule and Achillea Millefolium capsule, demographic and menstrual characteristic questionnaire and the visual Analog Scale will be given to eligible university students and asked them to complete it, in the first three days of menstrual cycle before taking medications.Then envelopes containing 250 mg Matricaria CHamomile capsule or capsule containing150 mg hydro alcoholic extract of Achillea Millefolium made by Kermanshah College of Pharmacy and named as code A or code B is distributed among participants by colleague researcher. Each code represents the existence of one of a variety of capsules inside the envelope and the researcher does not know which of the participants will use the envelope A or the envelope B. Only the pharmacist knows the nature of envelopes contain capsules. researcher, her colleague and participants are unaware of of the type of capsules, Blinding description: By sealing a sealed envelope; individuals may randomly build a Kermanshah Pharmacy School in the capsule group of 250 mg of Matricaria CHamomile, Kermanshah Pharmacy Department or in the group of Achillea Millefolium hydro-alcoholic capsules of Kermanshah, Color, size and aroma are quite similar and will be provided by the research collaborator. Apart from the pharmacist, the investigator or the participants will not know the nature of the medications. N/A Primary dysmenorrhea. Intervention 1: intervention group: Oral capsule 150 mg of Achillea Millefolium (constructed at Kermanshah Pharmacy Faculty) is takan every 8 hours after meal during the first 3 days of menstruation in the first and second cycles of their menstruation. Intervention 2: Control group: Oral capsule 250 mg of Matricaria CHamomile (constructed at Kermanshah Pharmacy Faculty) is taken every 8 hours after meal during the first 3 days of menstruation in their first and second cycle of menstruation. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information
public Shiva Radtar
Kurdistan University of Medical Sciences, Pasdaran Blvd
Sanandaj Iran (Islamic Republic of) ۶۶۱۷۷۱۵۱۷۵ +98 87 3366 4600 Shivaradfar53@gmail.com Kurdistan University of Medical Sciences scientific Laila Hashemi nasab
Kurdistan University of Medical Sciences, Pasdaran Blvd
Sanandaj Iran (Islamic Republic of) ۶۶۱۷۷۱۵۱۷۵ +98 87 3366 4600 hasheminasab.l.2014@gmail.com Kurdistan University of Medical Sciences Iran (Islamic Republic of) Be single Their menstruation start at the age of 11 to 17 Regular menstrual cycles every 21-35 days A score of 4 to 10 for menstrual pain according to the visual analogue scale Volunteered to participate in the study no limit no limit Female Have Abnormal bleeding Have history of any Herbal allergy Have Epilepsy Have Coagulation disorder Have Allergic asthma Have Digestive diseases Have Liver disease Have Renal disease Have Ovarian cyst Have Myoma Have pelvic tumor Have Endometriosis Consume Benzodiazepines Consume Barbiturates Consume Narcotics ConsumeTricyclic antidepressants Consume Anticoagulants Consume Theophylline Consume Steroid hormones drugs Oral contraceptive pills in the last three months were consumed Consume Alcohol Known Mental illness Have Pelvic inflammatory disease N94.4 Primary dysmenorrhea Treatment - Drugs Treatment - Drugs intervention group: Oral capsule 150 mg of Achillea Millefolium (constructed at Kermanshah Pharmacy Faculty) is takan every 8 hours after meal during the first 3 days of menstruation in the first and second cycles of their menstruation. Control group: Oral capsule 250 mg of Matricaria CHamomile (constructed at Kermanshah Pharmacy Faculty) is taken every 8 hours after meal during the first 3 days of menstruation in their first and second cycle of menstruation. Primary dysmenorrhea intensity. Timepoint: Before intevention، 1, 2, 4, 6 hours after intervention. Method of measurement: Visulal Analogue Scale. The amount of menstrual bleeding. Timepoint: Before intervention and at the end of the third day of the first cycle and the second cycle of menstruation, after taking the Matricaria CHamomile capsule and Achillea Millefolium capsule. Method of measurement: Pictorial blood assessment chart. Side effects of taking the Matricaria CHamomile capsule and Achillea Millefolium capsule. Timepoint: At the end of the third day of the first cycle and the second cycle of menstruation, after taking the Matricaria CHamomile capsule and Achillea Millefolium capsule. Method of measurement: Questionnaire. The number of menstruation days. Timepoint: Before intervention and at the end of the second menstrual cycle after intervention. Method of measurement: The questionnaire based on the number of menstrual days. Side effects of taking the Matricaria CHamomile capsule and Achillea Millefolium capsule. Timepoint: At the end of the second menstrual cycle after intervention. Method of measurement: Questionnaire. Kurdistan University of Medical Sciences Approved 2018-02-19 Ethics committee of Kurdistan University of Medical Sciences Kurdistan University of Medical Sciences; Pasdaran Blov sanandaj Kurdistan Iran (Islamic Republic of)