IRCT20111217008436N4 IRCT 2018-03-01 Kerman University of Medical Sciences Radiotherapy in Multiple sclerosis patients Evaluation of low dose radiotherapy on hypophyses in multiple sclerosis patients 2018-04-21 anticipated 10 Complete https://irct.ir/trial/28302 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Other design features: Nothing: don't blinded. 0 (exploratory trials) Multiple Sclerosis. Radiotherapy Technique: all the patients will be treated in supine position. Thermoplastic pillows and masks will be used to fix patients. Having placed the required markers, all patients will go through brain CT-Scan imaging at slice thickness of 5 mm. These images will be uploaded to ISOgray treatment planning application for a 3D treatment plan. The treatment field will include the sellar region plus a margin of 1 cm. We will take pains not to involve the cranial nerve and tract, as far as possible. To this end, shield will be applied in special cases. All patients will be treated with lateral and parallel opposite fields, at a daily dose of 2 Gray for 5 consecutive days, totally 10 Gray. A 6-MV linear accelerator will be used for the treatment.. No - There is not a plan to make this available Justification or reason for not sharing IPD is It includes the patients information and the information should be kept secret