]>
IRCT20170206032417N3 IRCT 2017-12-27 Oroumia University of Medical Sciences Effect of Whole Grain Diet on Non-Alcoholic Fatty Liver The effect of a diet enriched with whole grains or bran-contained cereals on liver echogenicity, liver function markers, anthropometry, insulin resistance, blood pressure and lipid profile in patients with nonalcoholic fatty liver disease 2017-06-24 anticipated 94 Complete https://irct.ir/trial/28269 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Parallel controlled randomized, Blinding description: In this one-sided study, only participants are unaware of the allocation of study groups. N/A Non-alcoholic fatty liver. Intervention 1: Intervention group: In this study, people in the intervention group after become aware of foods that are considered as whole grains,for 3 months will change their daily intake of cereals from refined grain to whole grains or grains with bran. in order to provide at least four serving of whole grains, And they will be asked to not change their physical activity during this time. Intervention 2: Control group: In this study, individuals in the control group were asked to take their usual daily intake of cereals for 3 months and not to change their physical activity. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is I have not decided yet.
public Dr. Mohammad Alizadeh
Nutrition Department, Faculty of Medicine, College of Medicine, Urmia University of Medical Science, 11th km of Nazloo Road, Urmia
Urmia Iran (Islamic Republic of) 5714783734 +98 44 3275 2375 alizadeh.m@umsu.ac.ir Oroumia University of Medical Sciences scientific Dr. Mohammad Alizadeh
Nutrition Department, Faculty of Medicine, College of Medicine, Urmia University of Medical Science, 11th km of Nazloo Road, Urmia
Urmia Iran (Islamic Republic of) 5714783734 +98 44 3275 2375 alizadeh.m@umsu.ac.ir Oroumia University of Medical Sciences Iran (Islamic Republic of) Age range over 18 years old in both sexes Non-alcoholic fatty liver disease detected by ultrasound 18 years 60 years Both Alcohol consumption or history Positive serology-hepatitis A-B-C Pregnancy and lactation during the study Diabetes Hypothyroidism Psychopathy kidney Diseases People who regularly receive at least half the daily cereals they consume from whole grains A major change in lifestyle K76.0 Fatty (change of) liver, not elsewhere classified Treatment - Other Other Intervention group: In this study, people in the intervention group after become aware of foods that are considered as whole grains,for 3 months will change their daily intake of cereals from refined grain to whole grains or grains with bran. in order to provide at least four serving of whole grains, And they will be asked to not change their physical activity during this time. Control group: In this study, individuals in the control group were asked to take their usual daily intake of cereals for 3 months and not to change their physical activity. Weight. Timepoint: At weeks 0,12. Method of measurement: Scale, kg. Triglyceride. Timepoint: At weeks 0, 12. Method of measurement: Enzymatic method, mg\dl. Total cholesterol. Timepoint: At weeks 0,12. Method of measurement: Enzymatic method, mg\dl. LDL cholesterol. Timepoint: At weeks 0 ,12. Method of measurement: (LDL= Total cholestrol – (HDL+ TG/5)). HDL cholesterol. Timepoint: At weeks 0,12. Method of measurement: Enzymatic method, mg\dl. Fasting blood sugar. Timepoint: At weeks 0,12. Method of measurement: Enzymatic method, mg\dl. Serum insulin. Timepoint: At weeks 0,12. Method of measurement: Radioimmunoassay. Alanine Aminotransferase. Timepoint: At weeks 0,12. Method of measurement: Enzymatic method, IU\ Lit. Aspartat transaminase. Timepoint: At weeks 0, 12. Method of measurement: Enzymatic method, IU\ Lit. Gamma Glutamyl transferase. Timepoint: At weeks 0,12. Method of measurement: Enzymatic method , IU\ Lit. Hepatic steatosis. Timepoint: Before intervention and three months intervention. Method of measurement: Ultrasonography. Systolic blood pressure. Timepoint: At weeks 0 ,12. Method of measurement: Mercury sphygmomanometer, mmhg. Diastolic blood pressure. Timepoint: At weeks 0, 12. Method of measurement: Mercury sphygmomanometer, mmhg. Height. Timepoint: Before intervention. Method of measurement: Stadiometer, mm. Body mass index. Timepoint: At weeks 0 ,12. Method of measurement: Weight(kg)\[height(m)]2 , kg\m2. Oroumia University of Medical Sciences Approved 2016-10-26 Urmia University of Medical Sciences Urmia University of Medical Sciences,orjans valley, Resalat boulevard Urmia West Azarbaijan Iran (Islamic Republic of)