<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20171031037142N2</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2018-02-12</date_registration>
      <primary_sponsor>Mashhad Ferdowsi University</primary_sponsor>
      <public_title>The effect of combination training and flax on menopausal complications</public_title>
      <acronym></acronym>
      <scientific_title>The effect of combined training with and without consuming the flaxseed ،  on the estrogen hormone, also on the Lipid profile and insulin resistance of postmenopausal women</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2016-02-29</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>30</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/27557</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: To determine the subjects in the training group and the exercise group with supplementation, from 1 to 30, it was written on small sheets and placed inside the box. Individuals extracted a number from the inside of the box before the first training session, if the desired number was paired, the person in the training group and, if the number was the one, the person was supplemented in the training group.</study_design>
      <phase>N/A</phase>
      <hc_freetext>In this study, the disease has not been studied and the subjects are healthy.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: combined training (The aerobic exercise was preformed with the intensity of 60 to 80 percent of the maximal heart rate and the resistance exercise with 4moves bench presses, wide grip last pull down, leg extension and lying leg curls with the intensity of 60 to 80 percent of a maximal repetition). Intervention 2: Intervention group: combined training(The aerobic exercise was preformed with the intensity of 60 to 80 percent of the maximal heart rate and the resistance exercise with 4moves bench presses, wide grip last pull down, leg extension and lying leg curls with the intensity of 60 to 80 percent of a maximal repetition)plus flaxseed (using 25 grams of the milled flaxseed  ).</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
All individual data of the participants in this study can be subscribed to after being unidentifiable

When:
Start the access period 3 months after printing the results

To whom:
Researchers working in academic institutions and health centers

Conditions:
Use data and research results to help the community and conduct further research

Where to obtain:
Email jahanshiri.nasrin@yahoo.com

How to obtain:
After receiving the email and ensuring that the reason for the request is one month

Comments:
No specific explanation</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Jahanshiri Nasrin</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Valiasr Township, Laleh 2, No. 12</address>
        <city>Torbat Heidarieh</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>9516143459</zip>
        <telephone>+98 51 5229 9300</telephone>
        <email>jahanshiri.nasrin@yahoo.com</email>
        <affiliation>Mashhad Ferdowsi University</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Jahanshiri Nasrin</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Valiasr Township, Laleh 2, No. 12</address>
        <city>Torbat Heidariyeh</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>9516143459</zip>
        <telephone>+98 51 5229 9300</telephone>
        <email>jahanshiri.nasrin@yahoo.com</email>
        <affiliation>Mashhad Ferdowsi University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>One year since the last menstruation,
having a body mass index of 25-30 kg / m2,
having a fat percentage of over 25%,</inclusion_criteria>
      <agemin>50 years</agemin>
      <agemax>60 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>not using hormone therapy
and not having regular exercise in the last 6 months</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: combined training (The aerobic exercise was preformed with the intensity of 60 to 80 percent of the maximal heart rate and the resistance exercise with 4moves bench presses, wide grip last pull down, leg extension and lying leg curls with the intensity of 60 to 80 percent of a maximal repetition)</i_keyword>
      <i_keyword>Intervention group: combined training(The aerobic exercise was preformed with the intensity of 60 to 80 percent of the maximal heart rate and the resistance exercise with 4moves bench presses, wide grip last pull down, leg extension and lying leg curls with the intensity of 60 to 80 percent of a maximal repetition)plus flaxseed (using 25 grams of the milled flaxseed  )</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Estrogen is a collection of female sex hormones that consists of three main types of 17 beta-estradiol, estradiol and sterile, and is the main cause of female secondary sex traits. In this study, estradiol levels, the most important type of estrogen, were measured by blood sampling. Timepoint: Blood samples were collected for measuring estrogen 24 hours before and 48 hours after the last exercise session. Method of measurement: To measure estrogen, the Japanese Toseh Kit was used.</prim_outcome>
      <prim_outcome>Insulin resistance is called insulin resistance, because of the inability of the body to produce enough insulin or the inability to use insulin effectively. Insulin resistance was measured using the Homa formula. Timepoint: Blood samples were collected for measuring insulin resistance 24 hours before and 48 hours after the last exercise session. Method of measurement: In order to measure insulin and glucose, a kit of Pars tazmon was used in Iran.</prim_outcome>
      <prim_outcome>Fat Profile: Blood lipids that appear in the form of triglycerides of cholesterol and lipoprotein (HDL, LDL). Timepoint: Blood samples were collected for measuring fat profile, 24 hours before and 48 hours after the last exercise session. Method of measurement: To determine the fat profile, the Pars azmon kits of Iran were used.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Mashhad Ferdowsi University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2017-12-03</approval_date>
        <contact_name>Mashhad Ferdowsi University</contact_name>
        <contact_address>Azadi Square, Ferdowsi University of Mashhad Mashhad Razavi Khorasan Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
