IRCT20170727035336N1 IRCT 2017-12-31 Vice chancellor for research, Tabriz University of Medical Sciences Randomized clinical trial ozone therapy on protruded lumbar disc herniation Randomized clinical trial ozone therapy on protruded lumbar disc herniation 2016-03-20 anticipated 100 Complete https://irct.ir/trial/26732 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 3 Diseases of the nervous system. Intervention 1: Injection of 250 micrograms of ozone in the disk space between the prosthetic disk Break the nucleotide proteoglycan so that the water is removed from the disk and the disk is collected. Intervention 2: Oral administration of a non-steroidal anti-inflammatory drug Naproxen 500 mg every 12 hours and bacullofen 10 mg muscle relaxant every 12 hours for 2 weeks. Undecided - It is not yet known if there will be a plan to make this available