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IRCT20170710035001N2 IRCT 2018-05-16 Mashhad University of Medical Sciences The effect of selenium on the thyroid nodule The effect of selenium on the size of thyroid nodules in euthyroid patients 2018-05-05 anticipated 60 Complete https://irct.ir/trial/26587 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Permuted block randomization with seal packet, Blinding description: Patients who obtaining informed consent were entered the study and randomly assigned to one of the two groups. patients, researchers and clinical personnel not aware from belonging to the each of the two groups with drug and placebo coding . 2-3 THYROID NODULE. Intervention 1: Intervention group: Edible selenium capsule Use 200 micro grams per day for three months,Manufacturer of the century21 country of America. Intervention 2: Control group: Taking placebo(Wheat bran),similar capsules with selenium capsules and no effective ingredients,Use 200 micro grams per day for three months,manufacturing factory:Mashhad Pharmaceutical Faculty. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public masoud mohebbi
Mashhad, Imam Reza Hospital
Mashhad Iran (Islamic Republic of) 9177899191 +98 51 3802 2358 MohebbiM@mums.ac.ir Mashhad University of Medical Sciences scientific Masoud Mohebbi
Emam Reza hospital ,internal medicine ward
mashhad Iran (Islamic Republic of) 9177899191 +98 51 3802 2370 mohebbim@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) have a thyroid nodule measuring more than 1 cm in size or a multi nodular goiter with a nodule greater than 1 cm These patients should have normal cytology (in FNA thyroid) the serum levels of selenium should be in the normal range 20 years 65 years Both Pregnant women Thyroid nodule diagnosed as suspected or malignant in FNA If the patient is not satisfied with the continuation of the study, selenium intolerance E04.1 E04.1-E04.9 Treatment - Drugs Placebo Intervention group: Edible selenium capsule Use 200 micro grams per day for three months,Manufacturer of the century21 country of America Control group: Taking placebo(Wheat bran),similar capsules with selenium capsules and no effective ingredients,Use 200 micro grams per day for three months,manufacturing factory:Mashhad Pharmaceutical Faculty Thyroid nodule size. Timepoint: Before intervention, three months after intervention. Method of measurement: Sonography. Mashhad University of Medical Sciences Approved 2017-07-09 Mashhad University of Medical Sciences Mashhad Holy, End of Shahid Fakoori Boulevard, between Shahid Javan Square and Shahid Al-Shahidi square, Zanjan Health MASHHAD Razavi Khorasan Iran (Islamic Republic of)