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IRCT2017071034997N1 IRCT 2017-09-03 Bahonar University Effect of resistance exercise and suppelment leucine on the treatment of Sarcopenia The effect of 8 weeks of resistance training and leucine supplements on protein synthesis in old men bearing Sarcopenia 2017-02-19 anticipated 40 Complete https://irct.ir/trial/26586 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Sarcopenia. Intervention 1: The training group 8 weeks and each week 3 sessions of resistance training performed with a duration of 20- 45 minutes and intensity of 35- 70 % one repetition maximum and 48 hours of rest between sessions. Intervention 2: The supplement group consumes 3 grams of leucine per meal for 8 weeks and 3 sessions each week. Intervention 3: The exercise and supplements group for 8 weeks and each week 3 sessions of resistance training performed with a duration of 20- 45 minutes and intensity of 35- 70 % one repetition maximum and 48 hours of rest between sessions. Also, 3 grams of leucine supplement consumes ratio 1/3, 1 hour before and 3 hours after exercise. Intervention 4: The control group consumes 3 grams of placebo per meal for 8 weeks and 3 sessions each week.
public Dr Mohsen Aminaie
Boulevard 22 Bahman, Kerman
Kerman Iran (Islamic Republic of) +98 343257624 maminai@yahoo.com Bahonar University scientific Dr Rohollah Nikooie
Boulevard 22 Bahman, Kerman
Kerman Iran (Islamic Republic of) +98 343257624 r_nikooie@uk.ac.ir Bahonar University Iran (Islamic Republic of) Criteria: Male; Aged 60- 65; Having general physical and mental health. Exclusion criteria: Having a history of chronic disease (heart failure, chronic obstructive pulmonary disease, kidney failure, cancer, diabetes, anemia and thyroid disease); Drug use or supplementation (such as corticosteroids and anabolic hormones); Inability to exercise; Having regular exercise history (3 times a week, more than 30 minutes). 60 years 65 years Male M62.84 Sarcopenia Other Other Other Other The training group 8 weeks and each week 3 sessions of resistance training performed with a duration of 20- 45 minutes and intensity of 35- 70 % one repetition maximum and 48 hours of rest between sessions. The supplement group consumes 3 grams of leucine per meal for 8 weeks and 3 sessions each week. The exercise and supplements group for 8 weeks and each week 3 sessions of resistance training performed with a duration of 20- 45 minutes and intensity of 35- 70 % one repetition maximum and 48 hours of rest between sessions. Also, 3 grams of leucine supplement consumes ratio 1/3, 1 hour before and 3 hours after exercise. The control group consumes 3 grams of placebo per meal for 8 weeks and 3 sessions each week. Protein synthesis. Timepoint: Before and 8 weeks after intervention. Method of measurement: Evaluation of nitrogen balance and muscle mass. Insulin. Timepoint: Before and after 8 weeks of intervention. Method of measurement: kamilonseans. Hand muscle strength. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Manual dynamometer. Walking speed. Timepoint: Before and after 8 weeks of intervention. Method of measurement: 4 metrs walking speed. Bahonar University Approved 2017-03-18 Ethics committee kerman university of medical sciences & health services Beginning of Ibn Sina street, Beginning of Jihad Boulevard, Four Way Somayeh Kerman Iran (Islamic Republic of)