]>
IRCT2017070434898N1 IRCT 2017-08-23 Vice Chancellor for research of Shahroud University of Medical Sciences Effect of Methocarbamol on postoperative pain following Inguinal Hernia surgery Effect of Methocarbamol on postoperative pain following Inguinal Hernia surgery 2016-03-20 anticipated 72 Complete https://irct.ir/trial/26545 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2 Inguinal hernia. Intervention 1: Intervention group: Half an hour before the patient leave the recovery department, the intervention group will receive 500 mg intravenous Methocarbamol (5 cc methocarbamol diluted with 5 cc normal saline) and then they receive oral Methocarbamol, 1 g, every 8 hrs from 6 hours until 7 days after the operation. Intervention 2: Control group: Half an hour before the patient leave the recovery department, the control group will receive 10 cc intravenous normal saline. Then they receive oral placebo tablets (similar to metocarbamol tablets in shape) every 8 hours, from 6 hours until 7 days after the operation.
public Mahdi Karimi
Shahroud University of Medical Sciences, Hafte Tir square, Shahroud
Shahroud Iran (Islamic Republic of) ۳۶۱۴۷-۷۳۹۴۷ +98 23 3239 5054 info@shmu.ac.ir؛ mahdi.karimi@shmu.ac.ir Shahroud University of Medical Sciences scientific Naser Mogharabian
Shahroud University of Medical Sciences, Hafte Tir square, Shahroud
Shahroud Iran (Islamic Republic of) ۳۶۱۴۷-۷۳۹۴۷ +98 23 3239 5054 info@shmu.ac.ir؛ dr.mogharabian@yahoo.com؛ mahdi.karimi@shmu.ac.ir Shahroud University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Age between 15 to 55 years old؛ Weight less than 100kg؛ Class I,II American Anesthesiology Association؛ Patient satisfaction. Exclusion criteria: Co-morbid severe or chronic systemic disease such as Asthma, Cardio-Pulmonary, Renal and Hepatic disease; Drug abuse in patients; Evidence of allergic reactions to Methocarbamol, Ibuprofen and Pethidine؛ Patient dissatisfaction. 15 years 55 years Both K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene Treatment - Drugs Placebo Intervention group: Half an hour before the patient leave the recovery department, the intervention group will receive 500 mg intravenous Methocarbamol (5 cc methocarbamol diluted with 5 cc normal saline) and then they receive oral Methocarbamol, 1 g, every 8 hrs from 6 hours until 7 days after the operation. Control group: Half an hour before the patient leave the recovery department, the control group will receive 10 cc intravenous normal saline. Then they receive oral placebo tablets (similar to metocarbamol tablets in shape) every 8 hours, from 6 hours until 7 days after the operation. Pain. Timepoint: 1,6,12,24 hour After the operation, and also a week after the operation. Method of measurement: Visual Analogue Scale (VAS). Consumable Pethidine. Timepoint: Up to 24 hours after surgery. Method of measurement: Patient document. Consumable Ibuprofen. Timepoint: 1 to 7 days after surgery. Method of measurement: Interview with patient. Vice Chancellor for research of Shahroud University of Medical Sciences Approved 2016-01-25 Ethics committee of Shahroud University of Medical Sciences Shahroud University of Medical Sciences, Hafte Tir square, Shahroud Shahroud Iran (Islamic Republic of)