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IRCT2017071134841N2 IRCT 2017-09-02 Deputy Research of Ardabil University of Medical Sciences Comparison of the efficiency and side effects of morphine and diclofenac suppositories with intramuscular pethedine in controlling post operative pain in appendectomy and inguinal hernia Comparison of the efficiency and side effects of morphine and diclofenac suppositories with intramuscular pethedine in controlling post operative pain in appendectomy and inguinal hernia 2013-03-27 anticipated 75 Complete https://irct.ir/trial/26516 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 Condition 1: postoperative pain control in appendectomy. Condition 2: postoperative pain control in inguinal hernia. Intervention 1: In the first group, suppository morphine 10 mg was administered at hours 2 nd, 6th, 12th and 24th after surgery. Intervention 2: In the second group, diclofenac suppository was given 100 mg at 2 nd, 6th, 12th, and 24th hours after surgery. Intervention 3: In the control group or the third group, if the patient had postoperative pain and the patient had a pain score above 4, 50 mg intramusclar pethidine was used to control pain.
public Shahram Galiche Chi
Ardabil Complex Univesity, Daneshgah st, Ardabil
Ardabil Iran (Islamic Republic of) 5618985991 +98 45 3352 2247 Dr.AkhavanAkbari@Gmail.com; Dr.GhaziAhmad@Gmail.com Ardabil University of Medical Sciences scientific Dr.Ghodrat Akhavan Akbari
Ardabil Complex Univesity, Daneshgah st, Ardabil
Ardabil Iran (Islamic Republic of) 5618985991 +98 45 3352 2247 Dr.AkhavanAkbari@Gmail.com; Dr.GhaziAhmad@Gmail.com Ardabil University of Medical Sciences Iran (Islamic Republic of) Patients underwent appendectomy and inguinal hernia in the age group of 18-70 years. Pregnant women, patients with neurological disease or psychiatric disorders, with history of seizure, with acute or chronic kidney disease, history of gastrointestinal ulcer, drug users Psychotropic substances users or alchohol consumption and those with hemorrhoids or anus disorder were not included in the study. 18 years 70 years Both k35, k36, k40 Diseases of appendix Inguinal hernia Treatment - Drugs Treatment - Drugs Treatment - Drugs In the first group, suppository morphine 10 mg was administered at hours 2 nd, 6th, 12th and 24th after surgery. In the second group, diclofenac suppository was given 100 mg at 2 nd, 6th, 12th, and 24th hours after surgery. In the control group or the third group, if the patient had postoperative pain and the patient had a pain score above 4, 50 mg intramusclar pethidine was used to control pain. Pain. Timepoint: In the hours 2,6,12,24 after surgery. Method of measurement: To measure the final outcome of the study patient pain score was based on the visual analogue score criteria with metric roler ranged from zero to ten according to the variables table. Patients sedation score. Timepoint: during the 2 nd,6th,12th,24th hours after surgey. Method of measurement: to score the patients sedation ramsy sedation score was used. Nausea and vomiting. Timepoint: during the 2 nd,6th,12th,24th hours after surgey. Method of measurement: The amont of N&V were measured according to N&V score. Deputy Research of Ardabil University of Medical Sciences Approved 2013-04-28 The Ethics Committee of Ardabil University of Medical Sciences Ardabil Complex Univesity, Daneshgah st, Ardabil ardabil Iran (Islamic Republic of)