IRCT2017061434533N1 IRCT 2017-09-25 Vice Chancellor for Research of Social Welfare and Rehabilitation Sciences University. Effectiveness of Family-Based Interventions on Family Members of Bipolar Patients A Clinical Trial to assess the Effectiveness of Family-Based Interventions on Severity of Symptoms, Stigma, Caregiver Burden, Emotion Expression and Coping Styles among Family Members of Bipolar Patients. 2016-03-19 anticipated 60 Complete https://irct.ir/trial/26367 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: For randomization all patients who met inclusion and exclusion criteria will select and we specify a code to each patient. Through drawing randomly by a blind person to purpose of study, patients allocate to intervention and control group. 2-3 Bipolar Disorder. Intervention 1: Intervention Group: Family members will receive family- based psychotherapy within 3 10-member groups. Family based psychotherapy consists of 12 session. The duration of each session is 90 minutes. The sessions contain these topics: knowledge about the disease, bio-psycho-social model, symptoms of bipolarity, mood stabilizer medications, medication compliance, knowledge about mood swings, how to apply mood graphs, relation between mood and situations, family members as predisposing events, reviewing the level of activity, regulating restrictions before reaching problematic level, crisis management and problem solving, family members tension reduction practices and relapse prevention. Intervention 2: Control Group: It consist of family members of patients with bipolar spectrum disorders. They will not receive intervention. They only complete questionnaires on pretest, post test and follow-up.