IRCT2017090133941N18 IRCT 2017-10-29 Vice chancellor for research, Arak University of Medical Sciences Effect of combined magnesium and vitamin E supplementation in treatment of women with polycystic ovary syndrome Clinical trial of the effect of combined magnesium and vitamin E supplementation compared with the placebo on metabolic profiles in women with polycystic ovary syndrome 2017-10-16 anticipated 60 Complete https://irct.ir/trial/26060 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: To decrease potential confounding effects, after balanced blocked randomisation, all participants will be allocated into two treatment groups to take either supplements or placebo. Randomization will be done by the use of computer software, Blinding description: Randomization and allocation will be concealed from the researchers and participants until the final analyses are completed. Another person at Kosar outpatient clinic, who is not involved in the trial and not aware of random sequences, will be assigned the participants to the numbered bottles of capsules. 3 Polycystic ovary syndrome. Intervention 1: Intervention group: 250 mg magnesium (21st Century, Arizona, USA) and 400 IU vitamin E (Zahravi, Tabriz, Iran) daily for 12 weeks orally. Intervention 2: Control group: Placebo capsule (Barij Essence, Kashan, Iran), daily for 12 weeks orally. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available.