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IRCT20170508033868N2 IRCT 2018-05-01 Vice chancellor for research Mashhad University of Medical Sciences Comparison of the effect of hand reflexology and foot reflexology on periodic breast pain Comparison of the effect of hand reflexology and foot reflexology on mastalgia among female college student 2017-05-22 anticipated 90 Complete https://irct.ir/trial/26018 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Randomized and three groups, Randomization description: Among the five dormitories of Mashhad University of Medical Sciences, three dormitories were selected randomly (with a draw) for the control group, hand reflexology group and foot reflexology group. 2-3 mastalgia. Intervention 1: Control group: Without intervention, just in the last 14 days of the menstrual cycle, the duration of the period are recorded in the Daily pain registry table and the severity of periodic breast pain are assessed using pain visual scale. Intervention 2: Intervention group 1: Hand reflexology, Doing daily 8 minutes of reflexology massage zones including Breast, upper lymphatic and solar plexus, on hand(With the intensity that felt numb in the place) in the last 14 days of the menstrual cycle and filling daily forms. Intervention 3: Intervention group 2: foot reflexology, Doing daily 8 minutes of reflexology massage zones including Breast, upper lymphatic and solar plexus, on foot(With the intensity that felt numb in the place) in the last 14 days of the menstrual cycle and filling daily forms. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is According to the laws of Mashhad University of Medical Sciences

public Hamideh Safari

Faculty of Nursing and Midwifery, Doctora intersection, Shariati Square

Mashhad Iran (Islamic Republic of) 00 +98 51 3859 1511 safarih941@mums.ac.ir Mashhad University of Medical Sciences scientific Mahin Tafazoli

Faculty of Nursing and Midwifery, Doctora intersection, Shariati Square

Mashhad Iran (Islamic Republic of) 00 +98 51 3859 1511 tafazolim@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Filling out the written consent to participate in the research. Being a resident of the female' dormitory of Mashhad University of Medical Sciences. Age range of 15 -45 years. BMI range of 19.6 - 29. Having a regular menstruation cycle ranging from 21 to 35 days. Complaining of breast pain that occurred during the last 14 days of the menstrual cycle. Obtaining a minimum pain intensity score of 30-69 using the visual analogue scale. 15 years 45 years Female Being a professional athlete؛ Eating rich-fat diet or diet containing xanthine. Pregnant or intend to become pregnant during the study. Breastfeeding. Experience of bad events in the past three months. Using hormonal medications or contraceptive pills since the last three months. Using the medicine to relieve pain during the last two months. Using a specific method to relieve breast pain. History of breast cancer in herself or her first-degree relatives. History of suspected breast mass in examination, mammography, or ultrasound. History of surgery on the breast or injection of gel or fat Having wound or lesion in the hands or feet. Having specific illness. Presence of physical disabilities. Presence of abnormality in breast examination. N64.4 Mastodynia Diagnosis Treatment - Other Treatment - Other Control group: Without intervention, just in the last 14 days of the menstrual cycle, the duration of the period are recorded in the Daily pain registry table and the severity of periodic breast pain are assessed using pain visual scale. Intervention group 1: Hand reflexology, Doing daily 8 minutes of reflexology massage zones including Breast, upper lymphatic and solar plexus, on hand(With the intensity that felt numb in the place) in the last 14 days of the menstrual cycle and filling daily forms Intervention group 2: foot reflexology, Doing daily 8 minutes of reflexology massage zones including Breast, upper lymphatic and solar plexus, on foot(With the intensity that felt numb in the place) in the last 14 days of the menstrual cycle and filling daily forms. Duration of pain. Timepoint: Two periods before the intervention and two periods during intervention(after one and two intervention cycles). Method of measurement: Daily pain registry table. Intensity of pain. Timepoint: Two periods before the intervention and two periods during intervention(after one and two intervention cycles). Method of measurement: Pain visual Scale. Vice chancellor for research Mashhad University of Medical Sciences Approved 2017-05-24 Ethics committee of Mashhad University of Medical Sciences Quraishi Building, Daneshgah street, Doctora Intersection, Mashhad Mashhad Razavi Khorasan Iran (Islamic Republic of)