IRCT138808272731N1 IRCT 2010-02-16 Tarbait Modares University The evaluation of effect of acupressure on primary dysmenorrheal The evaluation of effect of acupressure on primary dysmenorrheal 2008-10-22 anticipated 200 Complete https://irct.ir/trial/2576 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: Inclusion criteria: age 18-21 years, having regular menstrual cycles (duration of 3-8 days and interval of 21-35 days). presence of moderate to severe pain i.e. a score of 4 or more on a wrong-Baker faces pain scale, presence of symptoms of liver channel, presence of fix or sharp pain in lower abdomen for 1-2 day prior to onset of menstruation, distension feel in abdomen and breast, presence of dark-colored menstruation with clotting, irritability or depression and sometimes sleeplessness prior to onset of menstruation, tongue with red-colored seed, worsening the pain with pressure on abdominal), no prior history of gynecological disease or abdominal or pelvic surgery, no pain during menstrual cycle or menstruation duration, 2 hours after meal Exclusion criteria: history of mental stress in last 6 month especially having moderate to severe level of depression (score of 19 or more in beck-21 inventory), taking analgesics during 4 hours before intervention, menstruation cycle lower than 25 days or more than 35 days, use of tobacco products, or alcohol, presence of verbal, audible, mental problems, heart disease, kidney disease, diabetes mellitus, asthma, hyperthyroid or hypothyroid, or respiratory disease, presence of scar or inflammatory disease in acupoint. N/A primary dysmenorrhea. Intervention 1: In the experiment group, acupressure done on liv3 point located two thumb-widths behind the skin-margin between the first (big) and second toes for 3-7 days before the onset of menstruation for 20 minutes and follow up for 4 menstruation cycles. Intervention 2: In the control group, acupressure done on placebo point located two thumb-widths behind the skin-margin between the first (big) and second toes for 3-7 days before the onset of menstruation for 20 minutes and follow up for 4 menstruation cycles.