IRCT2017030532881N1 IRCT 2017-06-15 Mashhad University of Medical Sciences Comparison the effect of persica and chlorhexidine mouthwash. Comparison the effect of persica and chlorhexidine mouthwash in reducing salivary and plaque streptococcus mutans in primary school children. 2016-09-22 anticipated 50 Complete https://irct.ir/trial/25512 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A dental caries. Intervention 1: in intervention group Persica mouthwash was prescribed for 25 children who have weak and moderate oral hygiene but high caries risk .mouthwash was diluted by pharmacist before prescription ,according to factory instruction .this means that one drop of Persica in one cc water and the children were asked to rinse twice a day with 15 mlit for 60 seconds. at baseline samples from saliva and plaque were collected. After one week use of mouthwashes the samples were repeated. The streptococcus mutans counts in saliva and plaque as well as saliva PH and plaque index were recorded in both times. Intervention 2: in control group 0.12% Chlorhexidine mouthwash was prescribed for 25 children who have weak and moderate oral hygiene but high caries risk and the children were asked to rinse once a day with 15 mlit for 60 seconds.at baseline samples from saliva and plaque were collected. After one week use of mouthwashes the samples were repeated. The streptococcus mutans counts in saliva and plaque as well as saliva PH and plaque index were recorded in both times.