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IRCT2017022232719N1 IRCT 2017-05-15 Vice chancellor for research,Sabzevar University of Medical Sciences The effect of Curcumin on serum lipid profiles and systemic inflammation in hemodialysis patients The effect of Curcumin on serum lipid profiles and systemic inflammation in hemodialysis patients 2017-04-25 anticipated 64 Complete https://irct.ir/trial/25418 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. N/A Hemodialyzied kidney desease patients. Intervention 1: Intervention group: 80 mg Sina Curcumin medicine ، once in day in during 2months . Intervention 2: Control group: placebo contains 0/5 mg starch ، is given once in day during two months.
public Doctor Koushki
Sabzevar University of Medical Sciences
Sabzevar Iran (Islamic Republic of) +98 51 4401 1370 kooshki.nutr@gmail.com Sabzevar University of Medical Sciences scientific Doctor Koushki
Sabzevar University of Medical Sciences
Sabzevar Iran (Islamic Republic of) +98 51 4401 1370 kooshki.nutr@gmail.com Sabzevar University of Medical Sciences Iran (Islamic Republic of) IInclusion criteria: The patient's tendency to participating in study and signing approval form؛ Having a history of at least 6 months of dialysis؛ age between 25-75 years old ؛ BMI between 18.5 to 30؛ Lack of infectious disease, particularly hepatitis؛ Avoiding the use of no steroidal anti-inflammatory drugs, Nicotinic Acid, estrogen, progesterone and Curcumin supplementation for at least one month before the start of the study؛ Lack of drug addiction؛ Lack of severe heart disease, liver failure and thyroid, severe gastrointestinal bleeding and peptic ulcer disease, cholelithiasis, pregnancy or lactation Exclusion criteria: Increasing of potassium in patients' blood during the study؛ unwilling to continue to participate؛Death of the patient؛ Performing kidney transplantation؛ Increasing in dose of anti-fat drugs؛ Changing patient's lifestyle or diet during the study؛ The use of herbal medicines for lipid lowering during the study؛ No adherence to study intervention of at least 9 tablets during two months of interference 25 years 75 years Both E18 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified Prevention Prevention Intervention group: 80 mg Sina Curcumin medicine ، once in day in during 2months . Control group: placebo contains 0/5 mg starch ، is given once in day during two months. Trigliceride، Cholestrol، LDL، HDL ، hs crp. Timepoint: Before entrances and after entrances. Method of measurement: Blood test. BUN، Cr، Serum Albumin ، Adequacy of Dialysis ، BMI. Timepoint: Before entrances and after entrance. Method of measurement: Blood test. Vice chancellor for research,Sabzevar University of Medical Sciences Approved 2017-02-08 Ethics committee of Sabzevar University of Medical Sciences Sabzevar University of Medical Sciences Sabzevar Iran (Islamic Republic of)