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IRCT2017012132081N2 IRCT 2017-04-03 Vice Chancellor for research of Ahvaz Jundishapur University of Medical Sciences Survey the effect of saffron on asthma Survey the effect of saffron supplementation on the antibody titer to heat-shock protein (HSP) 70, hsCRP and spirometry test in patients with moderate persistent allergic asthma 2017-04-20 anticipated 86 Complete https://irct.ir/trial/25081 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 1 moderate persistent allergic asthma. Intervention 1: Saffron consumer group which receiving 100 mg of saffron per day in capsule form (two 50 mg capsule per day). Drug producing center: growth center of Ahvaz Jundishapur University of medical sciences. Duration of drug consumption is 8 weeks. Intervention 2: Placebo consumer group: consumption two capsules per day which containing starch. Drug producing center: growth center of Ahvaz Jundishapur University of medical sciences. Duration of drug consumption is 8 weeks.
public Marzie Zilaee
Ahvaz-Jundishapur university of medical sciences
Ahvaz Iran (Islamic Republic of) 00986135715794 +98 61 3336 7543 zilaee.m@ajums.ac.ir Department of nutrition, paramedicine school scientific Marzie Zilaee
paramedicine school- ahvaz jundishapur university of medical sciences
Ahvaz Iran (Islamic Republic of) 00986135715794 +98 61 3336 7543 Zilaee.m@ajums.ac.irmarziezilae@gmail.com Department of Nutrition-paramedicine school- ahvaz jundishapur university of medical sciences Iran (Islamic Republic of) Inclusion criteria: age between 18 to 65 years old, moderate persistent allergic asthma (FEV1 between 40 to 60 percent) according to the physician and normal BMI (up to 27). Inclusion criteria dos not belong to the particular gender and include male and females. Exclusion criteria include smoking, diabetes, pregnancy and lactation, autoimmune disease, malignancies, gastrointestinal, liver and kidney disease, pneumonia and other pulmonary disease and Not wanting to continue cooperation 18 years 65 years Both Treatment - Drugs Placebo Saffron consumer group which receiving 100 mg of saffron per day in capsule form (two 50 mg capsule per day). Drug producing center: growth center of Ahvaz Jundishapur University of medical sciences. Duration of drug consumption is 8 weeks. Placebo consumer group: consumption two capsules per day which containing starch. Drug producing center: growth center of Ahvaz Jundishapur University of medical sciences. Duration of drug consumption is 8 weeks. Antibody titers to heat shock protein 70. Timepoint: Before and two months after intervention. Method of measurement: according to the Laboratory Measurement-ng/ml. FEV1, FVC, FEV1/FVC. Timepoint: Before and two months after intervention. Method of measurement: According to the results of the spirometer-scale:percent. HsCRP. Timepoint: Before and two months after intervention. Method of measurement: according to the laboratory measurement-mg/dl. Lipid profile. Timepoint: Before and two months after intervention. Method of measurement: according to the laboratory measurement-mg/dl. Blood presure. Timepoint: Before and two months after intervention. Method of measurement: according to the results of Sphygmomanometer-mmhg. Clinical variables and the patient's general status. Timepoint: Before and two months after intervention. Method of measurement: according to the Questionnaires completed by physician superspecialty. Vice Chancellor for research of Ahvaz Jundishapur University of Medical Sciences Approved 2017-03-07 Ethics committee of Ahvaz Jundishapur University of Medical Sciences Ahvaz. Golestan Bolvar. Jundishapur University of Medical Sciences. Research Assistance Ahvaz Iran (Islamic Republic of)