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IRCT2017022631642N1 IRCT 2017-02-26 Ardebil University of Medical Sciences The effects of Aminophyllin on recovery duration, postoperative shivering and PONV with elective general surgery Aminophyllin on postoperative shivering The effects of Aminophyllin on recovery duration, postoperative shivering and PONV with elective general surgery 2017-03-21 anticipated 88 Complete https://irct.ir/trial/24847 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. N/A Postoperative shivering. Intervention 1: 4 mg kg aminophylline in 10 mL of saline is diluted and infusion before surgery. Vital signs, duration of recovery, the degree of shivering and need to treatment shiveringin in recovery, nausea in recovery and 6,24 houre after surgery will be meaured and record . Intervention 2: Ten mL of saline is given before surgery Vital signs, duration of recovery, the degree of shivering and need to treatment shiveringin in recovery, nausea in recovery and 6,24 houre after surgery will be meaured and record . .
public Mohadeseh Esmailnejad
Ardebil University of Medical Sciences, Daneshgah St.
Ardebil Iran (Islamic Republic of) +98 44 3427 2643 m.esmaeil@arums.ac.ir Ardebil University of Medical Sciences scientific Dr. Masod Entezari
Ardebil University of Medical Sciences, Daneshgah St.
Ardebil Iran (Islamic Republic of) +98 45 3352 2083 m.entezari@arums.ac.ir Ardebil University of Medical Sciences Iran (Islamic Republic of) Patients with a history of cardiovascular, pulmonary, or thyroid disease; dysautonomia; fever; aminophylline intake within a day before surgery; and who received transplant, will leave from this study. All patientsl will enter referred for elective general surgery to Imam Khomeini hospital in Ardebil. 18 years 70 years Both T88.5 Other complications of anaesthesia Treatment - Drugs Placebo 4 mg kg aminophylline in 10 mL of saline is diluted and infusion before surgery. Vital signs, duration of recovery, the degree of shivering and need to treatment shiveringin in recovery, nausea in recovery and 6,24 houre after surgery will be meaured and record . Ten mL of saline is given before surgery Vital signs, duration of recovery, the degree of shivering and need to treatment shiveringin in recovery, nausea in recovery and 6,24 houre after surgery will be meaured and record . . Shivering. Timepoint: At the time of recovery. Method of measurement: Scale: 0 = no shivering; 1 = no visible muscle activity but piloerection, peripheral vasoconstriction, or both are present (other causes excluded); 2 = muscular activity in only one muscle group; 3 = moderate muscular activity in more than one muscle group but no generalized shaking; 4 = violent muscular activity that involves the whole body. Nausea. Timepoint: At the time of recovery, 6 and 24 hours after surgery. Method of measurement: Scale: no nausea = 0; mild nausea = 1; moderate nausea = 2; severe nausea= 3. Ardebil University of Medical Sciences Approved 2016-12-11 Ardebil University of Medical Sciences Ardebil University of Medical Sciences, Daneshgah st. Ardabil Iran (Islamic Republic of)