IRCT201605201155N24 IRCT 2016-08-30 Vice chancellor for research of Guilan University of Medical Sciences Assessment of efficacy of N-Acetylecysteine plus standard quadruple therapy regimen in comparison to standard quadruple therapy regimen for H. pylori infection eradiacation Assessment of efficacy of N-Acetylecysteine plus standard quadruple therapy regimen in comparison to standard quadruple therapy regimen for H. pylori infection eradiacation 2016-08-22 anticipated 46 Complete https://irct.ir/trial/247 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2-3 Helicobacter pylori. Intervention 1: The experimental group was given amoxicillin (capsules, 1000 mg) bid (with breakfast and dinner), clarithromycin (capsules, 500 mg) bid (with breakfast and dinner), and omeprazole (capsules, 20 mg) bid (before breakfast and dinner), plus NAC 600 mg bid. Intervention 2: (The control group was given amoxicillin/clarithromycin/omeprazole the same as experimental group, plus placebo.In patients without peptic ulcer, omeprazole 20 mg once daily was continued for 2 weeks.