IRCT2016112631116N1 IRCT 2017-01-07 Shiraz University of Medical Sciences Effect of simvastatin gel on periodontitis Clinical evaluation of the effect of allograft alone, or in combination with simvastatin gel in the treatment of mandibular class II furcation defects in human 2015-11-22 anticipated 10 Complete https://irct.ir/trial/24541 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Furcation involvement class 2 mandible molars (periodontitis). Intervention 1: Intervention group: allograft and membrane and simvastatin gel are used. After local anesthesia and incision in the target area, flap were reflected, debridemant was performed, then allograft with simvastatin gel put in the defect, membrane adapted on the defect and suture the flap. Intervention 2: Control group: allograft with placebo gel. After local anesthesia and incision in the target area, flap were reflected, debridemant was performed, then allograft put in the defect, membrane adapted on the defect and suture the flap.