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IRCT2017052930680N4 IRCT 2017-10-02 Research Department, Shahed University The Effect Of Combination of Drugs Acetaminophen, Aspirin, Caffeine (AAC) on Migraine Headaches Comparison the Effects of Combined Drugs Acetaminophen,Aspirin,Caffeine With Ibo Profen On Acute Attacks of Migraine Headaches 2017-03-20 anticipated 60 Complete https://irct.ir/trial/24300 interventional Randomization: N/A, Blinding: Double blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Headache. Both test and control are the same .Each migrainous patients takes drugs for four times .At first and second attack iboprofen and acetaminophen,aspirin and caffeine for 3rd and 4th attacks and each time patients are evaluated with standard scales for pain.
public Siamak Afshinmajd
Entrance of Tehran -Qom express way, Shahed University
Tehran Iran (Islamic Republic of) +98 21 5121 3092 afshin@shahed.ac.ir Medicine Faculty ,Shahed University scientific Siamak Afshinmajd
Keshavarz Bld, Italia Street, Tehran.
Tehran Iran (Islamic Republic of) +98 21 8896 9438 safshinmajd@yahoo.com Shahid Mostafa Khomeini Hospital Iran (Islamic Republic of) Inclusion Criteria; Migraine headache according to criteria of international headache society Informed consent of patients for use of analgesics in acute attack of headaches Age between twenty to forty-five years old Exclusion Criteria; Gastro intestinal problems Other types of headaches such as cluster,tension,.... Chronic pain in other parts of body Chronic use of analgesics or opium Past history of psychiatric problems Allergy to drugs which are used in the study 20 years 45 years Both G-43 MIGRAINE Treatment - Drugs Both test and control are the same .Each migrainous patients takes drugs for four times .At first and second attack iboprofen and acetaminophen,aspirin and caffeine for 3rd and 4th attacks and each time patients are evaluated with standard scales for pain Pain. Timepoint: Before, Two and six hours after taking drugs each time and four time for each patient. Method of measurement: BS-11/11-Point box scale/. Pain. Timepoint: six hours after taking each drug one time and two time for each patient. Method of measurement: BRS-6/6-point behavioral rating scale. Urticaria,Pruritus and redness of skin. Timepoint: Instantly after alarm of the patient. Method of measurement: Observation and consultation with proper specialist. Research Department, Shahed University Approved 2017-04-05 Ethical Committee of Shahed University Entrance of Tehran - Qom highway Tehran Iran (Islamic Republic of)