IRCT20161026030525N2 IRCT 2020-09-13 Vice Chancellor for Research, Ahvaz Jundishapur University of Medical Sciences of Medical Sciences Efficacy of oral probiotic in reducing of duration of diarrhea in children with acute colitis: a double blind randomized placebo controlled trial Efficacy of oral probiotic in reducing of duration of diarrhea in children with acute colitis: a double blind randomized placebo controlled trial 2016-07-05 anticipated 94 Complete https://irct.ir/trial/24229 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Assignment of patients to each intervention and control groups will be done using winpepi software (random block method) and using six blocks, Blinding description: Probiotic powder and placebo are similar in appearance, taste and smell. Probiotics and placebo, which are completely similar, were placed in packages in a sterile method and assigned a single code to each package. The patient and the questionnaire filler were unaware of the type of drug in the package. 1-2 Acute colitis. Intervention 1: Intervention group: Supportive measures including intravenous or oral fluid therapy (ORS solution), antibiotic therapy (azithromycin suspension 12 mg per kg on the first day and then 6 mg per kg daily and the duration of treatment is 5 days). And zinc (zinc sulfate syrup for children under 6 months of age 10 mg daily and over 6 months of age 20 mg daily) in addition to the above treatments bulardi saccharomycesides in the form of probiotic capsules under the brand name yomogi 250. Children over 3 months receive a 250 mg capsule every 12 hours for up to 5 days (15) and in case of vomiting, the drug will be returned to the patient 15 minutes later. Intervention 2: Control group: The control group includes supportive measures including intravenous or oral fluid therapy (ORS solution), antibiotic therapy (azithromycin suspension 12 mg per kg on the first day and then 6 mg per kg daily and the duration of treatment is 5 days). And zinc (zinc sulfate syrup for children under 6 months of age 10 mg daily and over 6 months of age 20 mg daily). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information