IRCT2016091929873N1 IRCT 2016-11-05 Isfahan Research Department of Medical Sciences The effect of vitamin B6 in the prevention of postpartum depression Effect of prescribed vitamin B6 for depression among “mothers at risk for postpartum depression” during the third trimester at selected health care centers Isfahan city 2016. 2016-02-24 anticipated 80 Complete https://irct.ir/trial/23904 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. N/A postpartum depression. Intervention 1: Case group receive {2 tablets B6 (40mg; oral) daily; from week 28 till end pregnancy; after delivery1 tablet B6 (40mg; oral) daily for one month}. Every two weeks, Researcher phone calls to ensure, they were reminded of pills on phone and mentioned the subjects’ use of pill. Edinburgh postpartum depression questionnaires were completed by research’s units before intervention and 1.5 months after delivery. Intervention 2: Control group receive { placebo 2 tablets oral ; daily from week 28 till end pregnancy, after delivery receiving placebo 1 tablet oral ; daily for a month} . The Placebo tablet has 6.2 mm in diameter and 100 mg weight and made from corn starch. The placebo tablet is Simulated of vitamin tablet B6 Amin pharmaceutical factory. Every two weeks, Researcher phone calls to ensure, they were reminded of pills on phone and mentioned the subjects’ use of pill. Edinburgh postpartum depression questionnaires were completed by research’s units before intervention and 1.5 months after delivery.