IRCT2016090529710N1 IRCT 2016-09-30 Kashan University of Medical Scinces and Health Services Effect of oral and vaginal administration probiotic in treatment of women with vaginal candidiasis Effect of oral and vaginal administration probiotic in treatment of women with vaginal candidiasis 2016-07-20 anticipated 80 Complete https://irct.ir/trial/23813 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization will be done by simple method and using random numbers generated by computer software (Stat Trek software). In this method the computer selects random numbers. with consideration of numbers, the two groups are randomized, Blinding description: Placebo will be used to achieve participants,Care provider and investigators will be masking. The researchers and patients will be concealed until the final analyses by a trained staff. 2-3 Vulvovaginal Candidiasis. Intervention 1: Oral Fluconazol treatment with Oral probiotic capsules containing Lactobacillus acidophilus,Lactobacillus plantarum,Lactobacillus fermentum, Lactobacillus gasseri 1×10 9 colony are known as lactofem for once a day for 27 days(4 weeks) plus Vaginal probiotic capsules containing Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus gasseri, Lactobacillus plantarum 1×10 9colony are known as lacto Vage for once every night for 14days(4 weeks). Intervention 2: Oral Fluconazol treatment with Oral placebo for once a day for 27 days(4 weeks) plus Vaginal placebo for once every night for 14days(4 weeks). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available.