IRCT2016080229159N1 IRCT 2017-04-27 Vice Chancellor for research of Babol University of Medical Sciences The effect of acupressure on severity of pain and anxiety - Clinical trials The effectiveness of acupressure on pain and anxiety in cancer patients undergoing bone marrow aspiration and biopsy 2016-12-10 anticipated 90 Complete https://irct.ir/trial/23512 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Other design features: This study uses a sampling method, 90 patients were randomized into 3 groups of 30 blocks, a group of acupressure, placebo and one group studied the routine care. 2 neoplasm. Intervention 1: In the experimental group, acupressure will be applyin “Hugo” point or LI4 which is located in the hand, between the first and second metacarpal bones and the seventh heart or He7 which is located in the transverse fold of wrist which is directly in contact with flexor tendon, Carmen Ulnarys for 1 minute to will be done symmetrically on both hands. Intervention 2: In the placebo group, the acupressure will be performed on the same points at a distance of 1.5 cm from the main points,for 1 minute to will be done symmetrically on both hands that these points will be ineffective and will have no effect on anxiety and pain . Intervention 3: Control group, No procedure will be performed in the control group.