IRCT2016072929116N1 IRCT 2016-12-07 Vice Chancellor for research of Tehran University of Medical Sciences Comparing fluid therapy for kidney transplant surgery guided by PVI (Plethysmography Variability Index) monitoring and conventional fluid therapy in improving transplant kidney function Comparing fluid therapy guided by PVI (Plethysmography Variability Index) monitoring vs. conventional fluid therapy in improving transplant kidney function and blood lactate levels in kidney transplant patients 2015-09-23 anticipated 50 Complete https://irct.ir/trial/23485 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Individuals are assigned to control and intervention group randomly via a random numbers table. N/A End Stage Renal Failure. Intervention 1: In the intervention group we use PVI monitoring (plethysmography variablility index) to administer fluids during kidney transplantation surgery. We use the Masimo set PVI monitoring. Masimo, Irvine California. We use the device to guide the peri-operative fluid therapy during the surgery in the operating room. The PVI index is maintained between 10-13 by administering additional crystaloids. as the index rises above 13, 200 mililiters of crystaloids are adminstered and maintenance is given so that the index is always between 10 and 13. If the index is below 10, then all the crystaloids are held except half the maintenance need. Intervention 2: In the control group we administer fluids to the patients by the conventional liberal methods for transplant recipient patients. we give fluids freely to compensate for hemodynamic abnormalities and/or fluid loss and deficits and half the maintenance needs to the patients during surgery.