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IRCT2016071929004N1 IRCT 2016-10-12 Vice chancellor for research, Kerman University Of Medical Sciences The effect of dill vaginal cream on treatment of candida vaginitis The comparision effect of Anethum graveolens L. (dill) products on traditional medicine base with clotrimazole cream 1% on vaginal candidiasis. 2016-07-14 anticipated 105 Complete https://irct.ir/trial/23406 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Randomised(Blocked randomization), case control,double blind , study in single field and control with standard treatment. 2-3 vulvovaginal Candidiasis. Intervention 1: using one applicator of Essential oil of Anethum graveolens L. (Dill) vaginal cream (2%) every night for 7 nights. Intervention 2: using one applicator of Clotrimazole vaginal cream 1% every night for 7 nights . Intervention 3: using one applicator of total extract of dill vaginal cream (2%) every night for 7 nights .
public Zohreh Sarhadinejhad
Modiriat avenue , Traditional Medicine College
Kerman Iran (Islamic Republic of) 0098347615687644 00983433122020; 00983433122023; 00983431325720 z_sarhadinejhad@kmu.ac.ir; dr_isac1390@ yahoo.com Kerman University Of Medical Sciences scientific Dr Zohreh Salari
Afzalipoor Hospital, Emam Freeway.
Kerman Iran (Islamic Republic of) +98 343322225060 Zohreh_salari@yahoo.com; z_sarhadinejhad@kmu.ac.ir; dr_isac1390@ yahoo.com Kerman University Of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: sign and symptoms of vulvovaginal candidiasis; married women; between 18 to 65 years old; with positive sniff test; without pregnancy, without breast feeding, without chronic disease such as (kidney ,liver, cardiac disease and diabetes ), no existance of immunodeficiency nor complicated vaginal candidiasis on diagnosis of gynecologist and not using of systemic antibiotics and immunosuppressive drugs, or any vaginal drugs during the study and not using of systemic anti fungal drugs since 4 weeks ago. Exclusion criteria: side effects or drug reaction; pregnancy; menstruate; lack of patient's association. 18 years 65 years Female B37.3 Candidiasis of vulva and vagina Treatment - Drugs Treatment - Drugs Treatment - Drugs using one applicator of Essential oil of Anethum graveolens L. (Dill) vaginal cream (2%) every night for 7 nights. using one applicator of Clotrimazole vaginal cream 1% every night for 7 nights . using one applicator of total extract of dill vaginal cream (2%) every night for 7 nights . Burning. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evaluation of clinical symptom's remission(burning) with VSQ (vulvovaginal symptom questionnaire). Itching. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evauation of clinical symptom's remission (itching) with VSQ (vulvovaginal symptom questionnaire). Vaginal discharge. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evaluation of clinical symptom's remission (vaginal discharge) with VSQ (vulvovaginal symptom questionnaire). Erithema. Timepoint: at the beginning and 10 days after intervention. Method of measurement: physical exam. Edema. Timepoint: at the beginning and 10 days after intervention. Method of measurement: physical exam. Sniff test outcome. Timepoint: at the beginning and 10 days after intervention. Method of measurement: vaginal smear. Vice chancellor for research, Kerman University Of Medical Sciences Approved 2016-07-13 Ethical Committee of Kerman University Of Medical Sciences Kerman University Of Medical Sciences Paradise, Haftbagh freeway. kerman Iran (Islamic Republic of)