IRCT2016062228586N1 IRCT 2016-09-28 Vice chancellor for research,Mashhad University of Medical Sciences Rosemary effect on the amount of menstrual bleeding and Primary dysmenorrhea Comparing the effects of rosemary and Mefenamic Acid Capsules of amount of menstrual bleeding and Primary dysmenorrhea 2016-07-22 anticipated 90 Complete https://irct.ir/trial/23165 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 3 Primary dysmenorrhea. Intervention 1: Control group: treated with mefenamic acid 250 mg every 8 hours for 2 menstrual cycle in the first three days of the menstrual cycle. Intervention 2: Intervention group: Rosemary If not treated with capsules for 2 menstrual cycle every 8 hours for the first three days of the menstrual cycle.

public Fahimeh Tahoonian Gholkhatmy

School of Nursing and Midwifery, Mashhad University of Medical Sciences, Ebnecina Avenue

Mashhad Iran (Islamic Republic of) +98 51 3225 0041 tahounehf931@mums.ac.ir School of Nursing and Midwifery, Mashhad University of Medical Sciences scientific Zahra Abedian

School of Nursing and Midwifery, Mashhad University of Medical Sciences, Ebnecina Avenue

Mashhad Iran (Islamic Republic of) +98 385981511 abedianz@mums.ac.ir School of Nursing and Midwifery, Mashhad University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Iran and is unmarried؛ The age of research units at least 18 years؛ have regular menstrual cycle؛ Pain a few hours before or at the same time occur with menstrual bleeding؛ Menstrual pain can take 3 days or less؛ The mean pain score on the visual analogue pain 40 to 70 mm؛ The past six months have severe psychological stress؛ Is not known medical illness؛ Do not use a particular drug؛ Is not special diet such as weight loss diet, obesity, vegetarian and water treatment؛ Do not use Tobacco or alcohol؛ Do not regular exercise; Do not have severe bleeding menstrual Exclusion criteria:The use of oral contraceptives or other steroid hormones؛ history of allergic reaction to mefenamic acid is consumed and rosemary؛ consume supplements. 18 years no limit Female N94.4 Primary dysmenorrhoea Treatment - Drugs Treatment - Drugs Control group: treated with mefenamic acid 250 mg every 8 hours for 2 menstrual cycle in the first three days of the menstrual cycle Intervention group: Rosemary If not treated with capsules for 2 menstrual cycle every 8 hours for the first three days of the menstrual cycle. Primary dysmenorrhea pain severity. Timepoint: 3 the first day of menstrual bleeding. Method of measurement: According to the Visual Analogue Scale (vas). The amount of menstrual bleeding. Timepoint: Menstrual bleeding period (7 days to 10 days menstrual cycle). Method of measurement: Hygam chart. Vice chancellor for research,Mashhad University of Medical Sciences Approved 2016-06-23 Mashhad University of Medical Sciences Ethics Committee Mashhad University of Medical Sciences, University Ave Mashhad Iran (Islamic Republic of)