IRCT2016091828188N3 IRCT 2017-06-13 Vice chancellor for research, Mazandaran University of Medical Sciences The investigation of theraputic effect of Bilinaster drop on neonatal hyperbiirubinemia Assessment of the effect of Bilinaster drop in the management of neonatal hyperbilirubinemia 2017-03-21 anticipated 100 Complete https://irct.ir/trial/22924 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: A computer software program is used to produce random numbers to allocate the medication and placebo to two groups. Adequate medication and placebo for each group will be placed in a special envelope marked with patient number and medication code. Thus, patients, doctor and assessor will have no knowledge of the nature of medication or group allocation, Blinding description: For blinding in this trial, similarity of interventions in the two treatment groups under study was anticipated. The placebo was prepared in similar packages, with all the same physical and similar properties (in terms of color, odor, consistency, etc.). The amount of ingestion and the number of times a day was the same in both products. The only difference in these two products was the code inserted (numerical code) on the package and the corresponding box. As the mothers and prescriber (nurse) and laboratory technician were not aware of the nature of these two products and the codes entered. 2 Neonatal jaundice. Intervention 1: Control group: The neonate with jaundice will receive placebo. The number of placebo drops per day is similar to the number of bilinaster drops. Intervention 2: Intervention group: The neonate with jaundice will receive Bilineaster drop which is manufactured by Sobhan Daru Company and is included manna of cotoneaster ( Shire-khesht). Bilineaster drop is prescribed about 1 g manna per day (15 drop) that is divided into 3 doses and at most until 5 days . No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information