IRCT2016060428188N2 IRCT 2016-12-26 Vice chancellor for research, Mazandaran University of Medical Sciences The investigation of theraputic effect of Cotoneaster drops on neonatal hyperbiirubinemia - Assessment of the effect of Cotoneaster drops in management of neonatal hyperbilirubinemia: a clinical trial 2016-10-22 anticipated 200 Complete https://irct.ir/trial/22923 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: Using blocking method, Randomization description: A computer software program is used to produce random numbers to allocate the medication and placebo to four groups, Blinding description: Group 1: The neonate with jaundice and the mother receive placebo. Group 2: The neonate with jaundice and the mother receive cotoneaster drops. Group 3: The neonate with jaundice receives cotoneaster drops and the mother receives placebo. Group 4: The infant with jaundice receives placebo and the mother receives cotoneaster drops. 2 Neonatal jaundice. Intervention 1: Intervention group 1 (Control): The neonate with jaundice and mother will receive placebo. The neonate with jaundice will receive placebo drops per day is similar to the number of cotoneaster drops. The mother will receive number of placebo drops per day is similar to the number of cotoneaster drops. Intervention 2: Intervention group 2: The neonate with jaundice and the mother both will receive cotoneaster drops. Mothers will receive 5 ml of cotoneaster drops every 8 hours for 5 days. Neonate will receive amount of 1 g of cotoneaster per day is divided into 3 doses until 5 days. Intervention 3: Intervention group 3: The neonate with jaundice will receive cotoneaster drops and the mother will receive placebo. The mother will receive number of placebo drops per day is similar to the number of cotoneaster drops. Neonate will receive amount of 1 g of cotoneaster per day is divided into 3 doses until 5 days. Intervention 4: Intervention group 4: The neonate with jaundice will receive placebo, and the mother will receive cotoneaster drops. The neonate will receive number of placebo drops per day is similar to the number of cotoneaster drops. Mothers will receive 5 ml of cotoneaster drops every 8 hours for 5 days. Yes - There is a plan to make this available What will be shared: All information will be published in an article. Details of the data are available at the request of the journal publisher and upon obtaining permission from the corresponding author. When: Data is available as an article as soon as the article is published with permission from the corresponding author. To whom: The data is provided as an article by the journal, and those who have access to the journal can use the data contained in the article, with the permission of the corresponding author. Conditions: The article's data is available in case of publication and is obtained by permission from the corresponding author. Where to obtain: The data is available to the journal and is accessible by obtaining permission from the corresponding author. How to obtain: Data is available from the journal after publication of the article. Comments: