]>
IRCT2016052928151N1 IRCT 2016-08-15 Vice chancellor for research, Fasa University of Medical Sciences The effects of decaffeinated green coffee on type II diabetes The effects of green decaffeinated coffee bean extract on type 2 diabetes mellitus: a randomized, double‐blind, placebo-controlled crossover trial 2016-08-22 anticipated 100 Complete https://irct.ir/trial/22897 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Supportive, Other design features: Random allocation will be done by using a table of random numbers. N/A Type II Diabetes. Intervention 1: Intervention group: Each Capsule contains 800 mg of decaffeinated green coffee extract and 50 percent chlorogenic acid . Two Capsules daily, one a half hour before breakfast and another a half hour before lunch with a full glass of water. Intervention 2: Control group: Each Capsule contains 800 mg of celloluse. Two Capsules daily, one a half hour before breakfast and another a half hour before lunch with a full glass of water.
public Farzad Roshanzamir
Ibn sina square, Fasa University of Medical Sciences
Fasa Iran (Islamic Republic of) +98 71 5331 6300 farzad.roshanzamer@yahoo.com; froshanzamer@gmail.com; farzadroshanzam@mail.mui.ac.ir Fasa University of Medical Sciences scientific Seyed Moeteza Safavi
Hezar Jarib St.
Isfahan Iran (Islamic Republic of) +98 31 3792 3168 safavimorteza@nutri.mui.ac.ir Isfahan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: diagnosis of type II diabetes during the last two years, aged 45 to 60 years, no weight loss during the last 6 months (less than 1 kg), avoiding the use of tobacco and alcohol Exclusion criteria: any change in medications or supplements, pregnancy, chronic kidney and liver disease, neuromuscular disease, failure to follow the prescribed diet (if food records during the study show the energy intake of 300 calories less or more than the amount specified). 45 years 60 years Both E11 Non-insulin-dependent diabetes mellitus Treatment - Drugs Placebo Intervention group: Each Capsule contains 800 mg of decaffeinated green coffee extract and 50 percent chlorogenic acid . Two Capsules daily, one a half hour before breakfast and another a half hour before lunch with a full glass of water. Control group: Each Capsule contains 800 mg of celloluse. Two Capsules daily, one a half hour before breakfast and another a half hour before lunch with a full glass of water. 2HPP. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. FBS. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. Weight. Timepoint: Beginning and end of each phase. Method of measurement: Carriage scales. Fetuin-A. Timepoint: Beginning and end of each phase. Method of measurement: ELISA. TG. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. Chol. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. LDL. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. HDL. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. Insolin. Timepoint: Beginning and end of each phase. Method of measurement: ELISA. HOMA-IR. Timepoint: Beginning and end of each phase. Method of measurement: Formola. GOT. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. GPT. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. ALK. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. Pr. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. ALB. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. Total billirobin. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. Direct billirobin. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer colorimetric method. Blood pressure. Timepoint: Beginning and end of each phase. Method of measurement: manometer. Waist circumference. Timepoint: Beginning and end of each phase. Method of measurement: Meter. Polyphenols. Timepoint: Beginning, Middle and end of each phase. Method of measurement: ELISA. HbA1C. Timepoint: Beginning and end of each phase. Method of measurement: Biochemical auto analyzer. Vice chancellor for research, Isfahan University of Medical Sciences Vice chancellor for research, Fasa University of Medical Sciences Vice chancellor for research, Isfahan University of Medical Sciences Approved 2016-04-26 Ethics committee of Fasa University of Medical Sciences Ibn sina square, Fasa University of Medical Sciences Fasa Iran (Islamic Republic of) Approved 2010-09-23 Ethics committee of Fasa University of Medical Sciences Ebe sina Square, Fasa University of Medical Sciences Fasa Iran (Islamic Republic of) Approved 2016-06-19 Ethics committee of Isfahan University of Medical Sciences Hezar Jarib St. Isfahan Iran (Islamic Republic of)