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IRCT2016052328008N1 IRCT 2016-07-20 Vice chancellor for research, Hamadan University of Medical Sciences Compared the effect of salicylic acid and Cryotherapy in the treatment of warts. Comparison of the effects of salicylic acid solutions versus Cryotherapy for the treatment of Extra genital wart on patients referred to the Farshchian hospital. 2016-04-20 anticipated 80 Complete https://irct.ir/trial/22818 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 Extragenital wart. Intervention 1: In group one, Cryotherapy was done with cotton swab dipped into liquid nitrogen and then applied on the warts for 5–20 seconds every week. If there is no improvement, Cryotherapy therapy was done once every two weeks and would be repeated up to five times. Intervention 2: In group two, 40% salicylic acid at the same illness that Cryotherapy is one to three other warts that are based on randomly selected was applied on the dry lesions with a cotton swab once daily for 8 weeks done. Both methods were done by a dermatologist.
public Abbasali Hesari
Farshchian Sinai Medical Center, Mirzadeh Eshhgi St, Hamadan
Hamadan Iran (Islamic Republic of) +98 81 2827 4184 alihesari39@yahoo.com Hamadan University Medical ScienceHamadan scientific Mohammad Reza Sobhan
Farshchian Sinai Medical Center, Mirzadeh Eshhgi St, Hamadan
Hamadan Iran (Islamic Republic of) +98 81 2827 4192 mreza_sobhan@yahoo.com Hamadan University Medical of ScienceHamadan Iran (Islamic Republic of) Inclusion criteria Extra genital wart; No an underlying disease such as diabetes; immunodeficiency; lack of medications that suppress the immune system a; more than 4 years of age and have at least two wart. Exclusion criteria Individuals younger than 4 years; lactation; ulceration of the skin in the treatment of active disease; coagulation disorders active; Intolerance to cold; immune system dysfunction and people with cold urticarial. no limit no limit Both A63.0 Anogenital (venereal) warts Treatment - Drugs Treatment - Drugs In group one, Cryotherapy was done with cotton swab dipped into liquid nitrogen and then applied on the warts for 5–20 seconds every week. If there is no improvement, Cryotherapy therapy was done once every two weeks and would be repeated up to five times. In group two, 40% salicylic acid at the same illness that Cryotherapy is one to three other warts that are based on randomly selected was applied on the dry lesions with a cotton swab once daily for 8 weeks done. Both methods were done by a dermatologist. The disappearance of or going Warts. Timepoint: At baseline, two weeks and, if no improvement up to 5 times in the Cryotherapy group. Method of measurement: Examination by dermatologist. Side effects, Such as erythema, pain and local irritation. Timepoint: 2-5-7 week. Method of measurement: Physical examination. . . Vice chancellor for research, Hamadan University of Medical Sciences Approved 2016-05-14 Ethics CommitteeHamadn University Medical ScienceHamadan Hamadan University of Medical Sciences, Pazoehsh Crossroad, Faehmide St. Hamadan Iran (Islamic Republic of)